Protein Information

Cytoscape View

UniProt AC / UniProt ID P62318 / SMD3_HUMAN
Protein Name Small nuclear ribonucleoprotein Sm D3
Gene Name Name: SNRPD3
Organism Homo sapiens (Human)

PRO ID PR:P62318
DAG View
PRO Name small nuclear ribonucleoprotein Sm D3 (human)
Definition A small nuclear ribonucleoprotein Sm D3 that is encoded in the genome of human.
Short Label hSNRPD3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P62318 (SNRPD3) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
S2 Phosphorylation PhosphoSitePlus
K8 Acetylation PhosphoSitePlus
K8 Sumoylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
C20 S-Nitrosylation dbSNO 25040305
Y62 Phosphorylation PhosphoSitePlus
R64 Methylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
K78 Acetylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
K87 Ubiquitination PhosphoSitePlus
S93 Phosphorylation PhosphoSitePlus
R97 Methylation PhosphoSitePlus
K99 Methylation PhosphoSitePlus
K104 Ubiquitination PhosphoSitePlus
R110 Methylation PhosphoSitePlus
R112 Methylation PhosphoSitePlus
R114 Methylation PhosphoSitePlus
R118 Methylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R64 S64 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K84 N84 Biomuta DOID:1324 / lung cancer [ cosmic ]
R112 G112 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
R118 C118 Biomuta DOID:10534 / stomach cancer [ tcga ]
R118 H118 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]