Protein Information

Cytoscape View

UniProt AC / UniProt ID P62316 / SMD2_HUMAN
Protein Name Small nuclear ribonucleoprotein Sm D2
Gene Name Name: SNRPD2
Organism Homo sapiens (Human)

PRO ID PR:P62316
DAG View
PRO Name small nuclear ribonucleoprotein Sm D2 (human)
Definition A small nuclear ribonucleoprotein Sm D2 that is encoded in the genome of human.
Short Label hSNRPD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P62316 (SNRPD2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378, 25944712
S2 Phosphorylation PhosphoSitePlus
K6 Acetylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
K8 Acetylation PhosphoSitePlus
K8 Sumoylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
S9 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T12 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K18 Ubiquitination PhosphoSitePlus
R19 Methylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
R61 Methylation PhosphoSitePlus
C63 S-Nitrosylation dbSNO 25040305, 2212679, 22126794, ...26338901
K71 Ubiquitination PhosphoSitePlus
K79 Acetylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
K92 Acetylation PhosphoSitePlus
K98 Acetylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
K118 Acetylation PhosphoSitePlus
K118 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation HPRD 20068231
S9 Phosphorylation HPRD 18669648, 19691289, 20068231
T12 Phosphorylation HPRD 19651622, 18669648, 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R19 Q19 Biomuta DOID:263 / kidney cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ tcga ]
S30 C30 Biomuta DOID:5041 / esophageal cancer [ icgc ]
K71 M71 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
K79 N79 Biomuta DOID:11934 / head and neck cancer [ tcga ]
S105 * Biomuta DOID:3571 / liver cancer [ icgc ]
S105 L105 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]