Protein Information

Cytoscape View

UniProt AC / UniProt ID P62280 / RS11_HUMAN
Protein Name 40S ribosomal protein S11
Gene Name Name: RPS11
Organism Homo sapiens (Human)

PRO ID PR:P62280
DAG View
PRO Name 40S ribosomal protein S11 (human)
Definition A 40S ribosomal protein S11 that is encoded in the genome of human.
Short Label hRPS11
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P62280 (RPS11) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378, 22223895
Y10 Phosphorylation PhosphoSitePlus
K12 Sumoylation PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
T15 Phosphorylation PhosphoSitePlus
K20 Acetylation PhosphoSitePlus
K21 Sumoylation PhosphoSitePlus
T28 Phosphorylation Q5S007 (LRRK2) PhosphoSitePlus 24725412
K30 Acetylation PhosphoSitePlus
K30 Sumoylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
Y36 Phosphorylation PhosphoSitePlus
Y37 Phosphorylation PhosphoSitePlus
K38 Acetylation PhosphoSitePlus   UniProt 19608861
K38 Sumoylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
K45 Acetylation PhosphoSitePlus   UniProt 19608861
K45 Methylation PhosphoSitePlus
K45 Sumoylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
T46 Phosphorylation Q5S007 (LRRK2) PhosphoSitePlus 24725412
K48 Sumoylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
T54 Phosphorylation Q5S007 (LRRK2) PhosphoSitePlus 24725412
Y55 Phosphorylation PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
K59 Sumoylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
C60 S-Nitrosylation dbSNO 26338901, 22126794
T63 Phosphorylation PhosphoSitePlus
S67 Phosphorylation PhosphoSitePlus   UniProt 23186163
R69 Methylation PhosphoSitePlus
S74 Phosphorylation PhosphoSitePlus
T78 Phosphorylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
R90 Methylation PhosphoSitePlus
Y92 Phosphorylation PhosphoSitePlus
Y95 Phosphorylation PhosphoSitePlus
R97 Methylation PhosphoSitePlus
K98 Acetylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
S110 Phosphorylation PhosphoSitePlus   UniProt 23186163
S114 Phosphorylation PhosphoSitePlus
C116 S-Nitrosylation dbSNO 26338901
C131 S-Nitrosylation dbSNO 22178444, 19366988, 18335467
K136 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K32 N32 Biomuta DOID:3571 / liver cancer [ icgc ]
K32 T32 Biomuta DOID:1793 / pancreatic cancer [ icgc, tcga ] DOID:10283 / prostate cancer [ cosmic ]
Y36 C36 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
R69 P69 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
Y95 * Biomuta DOID:1909 / melanoma [ tcga ]
Y95 C95 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
R97 H97 Biomuta DOID:363 / uterine cancer [ tcga ]
S114 P114 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
C116 F116 Biomuta DOID:1324 / lung cancer [ cosmic ]
K144 N144 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]