iPTMnet Report for P62280 (RPS11)
Protein Information
| UniProt AC / UniProt ID | P62280 / RS11_HUMAN |
| Protein Name | Small ribosomal subunit protein uS17 |
| Gene Name | Name: RPS11 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P62280 |
| PRO Name | 40S ribosomal protein S11 (human) |
| Definition | A 40S ribosomal protein S11 that is encoded in the genome of human. |
| Short Label | hRPS11 |
| Category | organism-gene |
P62280 (RPS11) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| A2 | Acetylation | score1 | UniProt | 19413330, 22814378, 22223895 | ||
| A9 | Methylation | score1 | IEDB | 32357974 | ||
| Y10 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K12 | Sumoylation | score1 | PhosphoSitePlus | |||
| K12 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T15 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K20 | Acetylation | score1 | PhosphoSitePlus | |||
| K21 | Sumoylation | score1 | PhosphoSitePlus | |||
| T28 | Phosphorylation | Q5S007 (LRRK2) | score2 | PhosphoSitePlus | 24725412 | |
| K30 | Acetylation | score1 | PhosphoSitePlus | |||
| K30 | Sumoylation | score1 | PhosphoSitePlus | |||
| K30 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K32 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y36 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y37 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K38 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K38 | Sumoylation | score1 | PhosphoSitePlus | |||
| K38 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K45 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K45 | Methylation | score1 | PhosphoSitePlus | |||
| K45 | Sumoylation | score1 | PhosphoSitePlus | |||
| K45 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T46 | Phosphorylation | Q5S007 (LRRK2) | score2 | PhosphoSitePlus | 24725412 | |
| K48 | Sumoylation | score1 | PhosphoSitePlus | |||
| K48 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T54 | Phosphorylation | Q5S007 (LRRK2) | score2 | PhosphoSitePlus | 24725412 | |
| Y55 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K58 | Acetylation | score1 | PhosphoSitePlus | |||
| K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K59 | Sumoylation | score1 | PhosphoSitePlus | |||
| K59 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C60 | Methylation | score1 | IEDB | 31844290 | ||
| C60 | S-Nitrosylation | score0 | dbSNO | 26338901, 22126794 | ||
| T63 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S67 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| R69 | Methylation | score1 | PhosphoSitePlus | |||
| S74 | Phosphorylation | score2 | IEDB PhosphoSitePlus | 32387766, 27869121 | ||
| T78 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
| R90 | Methylation | score1 | PhosphoSitePlus | |||
| Y92 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y95 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R97 | Methylation | score1 | PhosphoSitePlus | |||
| K98 | Acetylation | score1 | PhosphoSitePlus | |||
| K107 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S110 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S114 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C116 | Methylation | score1 | IEDB | 31844290 | ||
| C116 | S-Nitrosylation | score0 | dbSNO | 26338901 | ||
| C131 | Methylation | score1 | IEDB | 31844290 | ||
| C131 | S-Nitrosylation | score0 | dbSNO | 22178444, 19366988, 18335467 | ||
| K136 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T137 | O-Glycosylation | score2 | GlyGen | 34925382 | ||
| K144 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K153 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| A2 | V2 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K32 | T32 | Biomuta | DOID:10283 / prostate cancer [ cosmic, icgc ] | |
| Y36 | C36 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| R69 | P69 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| R90 | Q90 | Biomuta | DOID:1725 / peritoneum cancer [ cosmic ] | |
| Y95 | * | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| Y95 | C95 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| R97 | G97 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| R97 | S97 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
| R97 | H97 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S114 | P114 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| C116 | F116 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| T137 | A137 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K144 | N144 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] |
DAG View