iPTMnet Report for P61923 (COPZ1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P61923 / COPZ1_HUMAN
Protein Name Coatomer subunit zeta-1
Gene Name Name: COPZ1
Synonyms:COPZ;ORFNames:CGI-120,HSPC181;
Organism Homo sapiens (Human)

PRO ID PR:P61923
DAG View
PRO Name coatomer subunit zeta-1 (human)
Definition A coatomer subunit zeta-1 that is encoded in the genome of human.
Short Label hCOPZ1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P61923 (COPZ1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22223895
R25 Methylation PhosphoSitePlus
K29 Ubiquitination PhosphoSitePlus
T34 Phosphorylation PhosphoSitePlus
Y35 Phosphorylation PhosphoSitePlus
K39 Sumoylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K46 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
R149 Methylation PhosphoSitePlus
T159 Phosphorylation PhosphoSitePlus
S161 Phosphorylation phospho.ELM   PhosphoSitePlus 17525332
S166 Phosphorylation PhosphoSitePlus
K168 Ubiquitination PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO
S161 Phosphorylation HPRD 17525332


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036231 (hCOPZ1/Ac:1) acM1 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R25 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R25 Q25 Biomuta DOID:363 / uterine cancer [ icgc ]
K42 N42 Biomuta DOID:363 / uterine cancer [ icgc ]
K46 N46 Biomuta DOID:363 / uterine cancer [ icgc ]
T159 N159 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K168 T168 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K172 E172 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]