iPTMnet Report for P61758 (VBP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P61758 / PFD3_HUMAN
Protein Name Prefoldin subunit 3
Gene Name Name: VBP1
Synonyms:PFDN3;
Organism Homo sapiens (Human)

PRO ID PR:P61758
DAG View
PRO Name prefoldin subunit 3 (human)
Definition A prefoldin subunit 3 that is encoded in the genome of human.
Short Label hVBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P61758 (VBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K5 Acetylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
S7 Phosphorylation PhosphoSitePlus
C8 S-Nitrosylation dbSNO 26338901
K10 Ubiquitination PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K52 Acetylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K59 Acetylation PhosphoSitePlus   UniProt 19608861
K59 Ubiquitination PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
Y112 Phosphorylation PhosphoSitePlus
C113 S-Nitrosylation dbSNO 19483679
K114 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 V2 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:3571 / liver cancer [ cosmic ]
S7 I7 Biomuta DOID:9256 / colorectal cancer [ icgc ]
C8 G8 Biomuta DOID:1324 / lung cancer [ cosmic ]
K51 N51 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K70 T70 Biomuta DOID:3571 / liver cancer [ cosmic ]
K70 N70 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S97 T97 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S97 F97 Biomuta DOID:4159 / skin cancer [ cosmic ]
K153 M153 Biomuta DOID:1324 / lung cancer [ cosmic ]
S157 F157 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]