Protein Information

Cytoscape View

UniProt AC / UniProt ID P61604 / CH10_HUMAN
Protein Name 10 kDa heat shock protein, mitochondrial
Gene Name Name: HSPE1
Organism Homo sapiens (Human)

PRO ID PR:P61604
DAG View
PRO Name 10 kDa heat shock protein, mitochondrial (human)
Definition A 10 kDa heat shock protein, mitochondrial that is encoded in the genome of human.
Short Label hHSPE1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P61604 (HSPE1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO
K8 Acetylation PhosphoSitePlus
K8 Methylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
R15 Methylation PhosphoSitePlus
S21 O-Glycosylation GlyGen 20305658, 30444036, 31637018
S21 Phosphorylation PhosphoSitePlus
T27 Phosphorylation PhosphoSitePlus
K28 Ubiquitination PhosphoSitePlus
K36 Methylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
S37 Phosphorylation PhosphoSitePlus
K40 Acetylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
T45 Phosphorylation PhosphoSitePlus
S51 Phosphorylation HPRD   PhosphoSitePlus 19415658
S53 Phosphorylation PhosphoSitePlus
K56 Acetylation PhosphoSitePlus   UniProt 19608861
K56 Ubiquitination PhosphoSitePlus
S64 Phosphorylation HPRD   PhosphoSitePlus 20068231
K66 Ubiquitination PhosphoSitePlus
K70 Acetylation PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
T79 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
K80 Acetylation PhosphoSitePlus
K80 Sumoylation PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
K86 Acetylation PhosphoSitePlus   UniProt 19608861
K86 Ubiquitination PhosphoSitePlus
Y88 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
R92 Methylation PhosphoSitePlus
K99 Acetylation PhosphoSitePlus   UniProt 19608861
K99 Ubiquitination PhosphoSitePlus


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036161 (hHSPE1/Ac:1) acM1 PRO

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
M1 R1 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R15 Q15 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T45 R45 Biomuta DOID:4362 / cervical cancer [ tcga ] DOID:10534 / stomach cancer [ cosmic ] DOID:3571 / liver cancer [ icgc, tcga ]
S51 L51 Biomuta DOID:0060119 / pharynx cancer [ cosmic ]
S51 W51 Biomuta DOID:4362 / cervical cancer [ tcga ] DOID:263 / kidney cancer [ cosmic, icgc, tcga ]