iPTMnet Report for P61587 (RND3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P61587 / RND3_HUMAN
Protein Name Rho-related GTP-binding protein RhoE precursor
Gene Name Name: RND3
Synonyms:ARHE,RHO8,RHOE;
Organism Homo sapiens (Human)

PRO ID PR:P61587
DAG View
PRO Name Rho-related GTP-binding protein RhoE (human)
Definition A Rho-related GTP-binding protein RhoE that is encoded in the genome of human.
Short Label hRND3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P61587 (RND3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation Q13464 (ROCK1) PhosphoSitePlus   RLIMS-P 15775972, 27656111
K9 Ubiquitination PhosphoSitePlus
S11 Phosphorylation Q13464 (ROCK1) PhosphoSitePlus   RLIMS-P   Signor 15775972, 27656111
K13 Ubiquitination PhosphoSitePlus
S14 Phosphorylation PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
T173 Phosphorylation RLIMS-P 27656111
S210 Phosphorylation Q05513 (PRKCZ) PhosphoSitePlus   RLIMS-P 23622247
S218 Phosphorylation Q13464 (ROCK1) PhosphoSitePlus   RLIMS-P 23622247
S222 Phosphorylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus
T231 Phosphorylation PhosphoSitePlus
S240 Phosphorylation Q13464 (ROCK1) PhosphoSitePlus   RLIMS-P 23622247


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K9 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S210 L210 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S210 T210 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S227 * Biomuta DOID:4159 / skin cancer [ cosmic ]
T231 M231 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S240 I240 Biomuta DOID:10534 / stomach cancer [ cosmic ]