iPTMnet Report for P61353 (RPL27)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P61353 / RL27_HUMAN
Protein Name Large ribosomal subunit protein eL27
Gene Name Name: RPL27
Organism Homo sapiens (Human)

PRO ID PR:P61353
DAG View
PRO Name 60S ribosomal protein L27 (human)
Definition A 60S ribosomal protein L27 that is encoded in the genome of human.
Short Label hRPL27
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P61353 (RPL27) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K6 Ubiquitination PhosphoSitePlus
K9 Ubiquitination PhosphoSitePlus
K27 Acetylation PhosphoSitePlus   UniProt 19608861
K27 Ubiquitination PhosphoSitePlus
R36 Methylation PhosphoSitePlus
Y49 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
K73 Ubiquitination PhosphoSitePlus
Y75 Phosphorylation PhosphoSitePlus
Y77 Phosphorylation PhosphoSitePlus
T83 Phosphorylation PhosphoSitePlus
R84 Methylation PhosphoSitePlus
S86 Phosphorylation PhosphoSitePlus
K93 Acetylation PhosphoSitePlus   UniProt 19608861
K93 Ubiquitination PhosphoSitePlus
K98 Acetylation PhosphoSitePlus
K98 Sumoylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K107 Acetylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K117 Acetylation PhosphoSitePlus
K117 Sumoylation PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K128 Acetylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K133 Acetylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R36 C36 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R36 H36 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S86 T86 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K117 T117 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]