iPTMnet Report for P61289 (PSME3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P61289 / PSME3_HUMAN
Protein Name Proteasome activator complex subunit 3
Gene Name Name: PSME3
Organism Homo sapiens (Human)

PRO ID PR:P61289
DAG View
PRO Name proteasome activator complex subunit 3 (human)
Definition A proteasome activator complex subunit 3 that is encoded in the genome of human.
Short Label hPSME3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P61289 (PSME3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
K6 Acetylation PhosphoSitePlus
K6 Sumoylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
K12 Sumoylation PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
K14 Acetylation PhosphoSitePlus
K14 Sumoylation PhosphoSitePlus
K14 Ubiquitination PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus   UniProt 23186163
T23 Phosphorylation PhosphoSitePlus
S24 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
K36 Ubiquitination PhosphoSitePlus
K37 Ubiquitination PhosphoSitePlus
S75 Phosphorylation PhosphoSitePlus
Y84 Phosphorylation PhosphoSitePlus
K85 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
C92 Methylation IEDB 31844290
C92 S-Nitrosylation dbSNO 26338901
K100 Ubiquitination PhosphoSitePlus
K110 Methylation PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S111 Phosphorylation PhosphoSitePlus
K121 Methylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
C133 Methylation IEDB 31844290
T167 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
Y175 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
K195 Acetylation PhosphoSitePlus   UniProt 23612972
K195 Ubiquitination PhosphoSitePlus
K212 Methylation PhosphoSitePlus
Y214 Phosphorylation PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus   Signor   UniProt 25361978
S247 Phosphorylation O96017 (CHEK2) PhosphoSitePlus   Signor 25361978
S248 Phosphorylation PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T23 Phosphorylation HPRD 18452278
S24 Phosphorylation HPRD 18669648, 20068231, 18452278
Site PTM Type PTM Enzyme Score Source PMID
T23 Phosphorylation HPRD 18452278
S24 Phosphorylation HPRD 18669648, 20068231, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K36 N36 Biomuta DOID:363 / uterine cancer [ icgc ]
S111 G111 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]