Protein Information

Cytoscape View


UniProt AC / UniProt ID P61244 / MAX_HUMAN
Protein Name Protein max
Gene Name Name: MAX
Synonyms:BHLHD4;
Organism Homo sapiens (Human)

PRO ID PR:P61244
DAG View
PRO Name protein max (human)
Definition A protein max that is encoded in the genome of human.
Short Label hMAX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P61244 (MAX) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 21406692, 20068231
S2 Phosphorylation P68400 (CSNK2A1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 21406692, 17081983, 8247525, ...11535131, 7735324, 20068231, 8018564
S11 Phosphorylation P68400 (CSNK2A1) neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 21406692, 17081983, 8247525, ...11535131, 7735324, 20068231, 8018564
K24 Ubiquitination PhosphoSitePlus
K40 Acetylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
S42 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K66 Acetylation PhosphoSitePlus   UniProt 17217336
T68 Phosphorylation PhosphoSitePlus
Y70 Phosphorylation PhosphoSitePlus
Y73 Phosphorylation PhosphoSitePlus
R75 Methylation PhosphoSitePlus
K89 Methylation PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
S107 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y115 Phosphorylation PhosphoSitePlus
S118 Phosphorylation PhosphoSitePlus
S121 Phosphorylation PhosphoSitePlus
Y123 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
T124 Phosphorylation PhosphoSitePlus
S132 Phosphorylation PhosphoSitePlus
S138 Phosphorylation PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
S141 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
K153 Acetylation PhosphoSitePlus   UniProt 17217336
K154 Acetylation PhosphoSitePlus   UniProt 17217336
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation P68400 (CSNK2A1) HPRD   PRO 19413330, 19651622, 8018564, ...8247525, 11535131, 20068231
S11 Phosphorylation P68400 (CSNK2A1) HPRD   PRO 19413330, 19651622, 8018564, ...8247525, 11535131, 20068231
S49 Phosphorylation Q16539 (MAPK14) HPRD 7479834
Y123 Phosphorylation HPRD 15592455
S132 Phosphorylation HPRD 17081983
S138 Phosphorylation P68400 (CSNK2A1) HPRD 11535131
S140 Phosphorylation P68400 (CSNK2A1) HPRD 11535131, 19651622
S141 Phosphorylation P68400 (CSNK2A1) HPRD 11535131, 18452278
S142 Phosphorylation P68400 (CSNK2A1) HPRD 11535131
S144 Phosphorylation P68400 (CSNK2A1) , Q16539 (MAPK14) HPRD 11535131, 19651622, 18452278
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation P68400 (CSNK2A1) HPRD   PRO   PhosphoSitePlus 18691976, 8018564, 9115440, ...19651622, 20068231
S11 Phosphorylation HPRD   PRO   PhosphoSitePlus 8018564, 20068231, 17081983
S40 Phosphorylation Q16539 (MAPK14) HPRD 7479834
K57 Acetylation PRO 17217336
Y61 Phosphorylation PhosphoSitePlus
Y114 Phosphorylation HPRD   PhosphoSitePlus 15592455
S123 Phosphorylation HPRD 17081983
S129 Phosphorylation P68400 (CSNK2A1) HPRD 11535131
S131 Phosphorylation P68400 (CSNK2A1) HPRD 11535131, 19651622
S132 Phosphorylation P68400 (CSNK2A1) HPRD 11535131, 18452278
S133 Phosphorylation P68400 (CSNK2A1) HPRD 11535131
S135 Phosphorylation P68400 (CSNK2A1) , Q16539 (MAPK14) HPRD 11535131, 19651622, 18452278
K144 Acetylation PRO 17217336
K145 Acetylation PRO 17217336
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation P68400 (CSNK2A1) HPRD 19413330, 19651622, 20068231, ...9115440
S11 Phosphorylation P68400 (CSNK2A1) HPRD 19413330, 11535131, 9115440, ...8247525, 19651622, 20068231
S49 Phosphorylation Q16539 (MAPK14) HPRD 7479834
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation P68400 (CSNK2A1) HPRD 19413330, 19651622, 20068231, ...9115440
S11 Phosphorylation P68400 (CSNK2A1) HPRD 19413330, 11535131, 9115440, ...8247525, 19651622, 20068231
S49 Phosphorylation Q16539 (MAPK14) HPRD 7479834
Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation P68400 (CSNK2A1) HPRD 19413330, 19651622, 20068231, ...9115440
S11 Phosphorylation P68400 (CSNK2A1) HPRD 19413330, 11535131, 9115440, ...8247525, 19651622, 20068231
S49 Phosphorylation Q16539 (MAPK14) HPRD 7479834


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000025917 (hMAX/iso:long/Phos:1) pS2,pS11 PRO 8018564
PR:000025918 (hMAX/iso:short/Phos:1) pS2,pS11 PRO 8018564
PR:000025921 (hMAX/iso:short/Ac:1) acK57,acK144,acK145 PRO 17217336


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S42 I42 Biomuta DOID:363 / uterine cancer [ tcga ]
S42 N42 Biomuta DOID:363 / uterine cancer [ tcga ]
R75 * Biomuta DOID:363 / uterine cancer [ tcga ] DOID:1324 / lung cancer [ cosmic ]
Y123 C123 Biomuta DOID:1324 / lung cancer [ cosmic ]
T124 I124 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S142 L142 Biomuta DOID:3371 / chondrosarcoma [ cosmic ]