Protein Information

Cytoscape View

UniProt AC / UniProt ID P61225 / RAP2B_HUMAN
Protein Name Ras-related protein Rap-2b precursor
Gene Name Name: RAP2B
Organism Homo sapiens (Human)

PRO ID PR:P61225
DAG View
PRO Name Ras-related protein Rap-2b (human)
Definition A Ras-related protein Rap-2b that is encoded in the genome of human.
Short Label hRAP2B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P61225 (RAP2B) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Y4 Phosphorylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
Y40 Phosphorylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
T61 Phosphorylation PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
Y106 Phosphorylation PhosphoSitePlus
S127 Phosphorylation HPRD 20068231
K132 Ubiquitination PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K150 Ubiquitination PhosphoSitePlus
Y166 Phosphorylation PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K5 T5 Biomuta DOID:1324 / lung cancer [ cosmic ]
K31 N31 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
K42 E42 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]