iPTMnet Report for P61224 (RAP1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P61224 / RAP1B_HUMAN
Protein Name Ras-related protein Rap-1b precursor
Gene Name Name: RAP1B
ORFNames:OK/SW-cl.11;
Organism Homo sapiens (Human)

PRO ID PR:P61224
DAG View
PRO Name Ras-related protein Rap-1b (human)
Definition A Ras-related protein Rap-1b that is encoded in the genome of human.
Short Label hRAP1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P61224 (RAP1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Ubiquitination PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
Y32 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
Y40 Phosphorylation PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
K151 Acetylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
Y159 Phosphorylation PhosphoSitePlus
K174 Ubiquitination PhosphoSitePlus
S179 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 8463283, 27760305, 19651783, ...1696481, 1551424
S179 Phosphorylation P17612 (PRKACA) PhosphoSitePlus   Signor 1551424, 19651783
S179 Phosphorylation Q13976 (PRKG1) PhosphoSitePlus 1551424
S180 Phosphorylation PhosphoSitePlus   RLIMS-P 27760305
C181 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S179 Phosphorylation HPRD 12089143
S179 Phosphorylation P17612 (PRKACA) HPRD 12089143


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K5 R5 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S39 C39 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
S39 Y39 Biomuta DOID:363 / uterine cancer [ icgc ]
K42 R42 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K117 N117 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K128 E128 Biomuta DOID:10534 / stomach cancer [ cosmic ]