iPTMnet Report for P61086 (UBE2K)
Protein Information
UniProt AC / UniProt ID | P61086 / UBE2K_HUMAN |
Protein Name | Ubiquitin-conjugating enzyme E2 K |
Gene Name | Name: UBE2K Synonyms:HIP2,LIG; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P61086 |
PRO Name | ubiquitin-conjugating enzyme E2 K (human) |
Definition | A ubiquitin-conjugating enzyme E2 K that is encoded in the genome of human. |
Short Label | hUBE2K |
Category | organism-gene |
P61086 (UBE2K) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22814378, 22223895 | ||
K14 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
K14 | Sumoylation | score1 | PhosphoSitePlus | |||
K14 | Ubiquitination | score1 | PhosphoSitePlus | |||
K18 | Methylation | score1 | PhosphoSitePlus | |||
K18 | Ubiquitination | score1 | PhosphoSitePlus | |||
K24 | Ubiquitination | score1 | PhosphoSitePlus | |||
K28 | Ubiquitination | score1 | PhosphoSitePlus | |||
R40 | Methylation | score1 | PhosphoSitePlus | |||
T49 | Phosphorylation | score1 | PhosphoSitePlus | |||
K61 | Ubiquitination | score1 | PhosphoSitePlus | |||
K72 | Ubiquitination | score1 | PhosphoSitePlus | |||
K97 | Ubiquitination | score1 | PhosphoSitePlus | |||
K142 | Ubiquitination | score1 | PhosphoSitePlus | |||
S159 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K164 | Ubiquitination | score1 | PhosphoSitePlus | |||
K165 | Ubiquitination | score1 | PhosphoSitePlus | |||
S185 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K28 | E28 | Biomuta | DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ] | |
S159 | T159 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
K165 | R165 | Biomuta | DOID:363 / uterine cancer [ icgc ] |