iPTMnet Report for P61077 (UBE2D3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P61077 / UB2D3_HUMAN
Protein Name Ubiquitin-conjugating enzyme E2 D3
Gene Name Name: UBE2D3
Synonyms:UBC5C,UBCH5C;
Organism Homo sapiens (Human)

PRO ID PR:P61077
DAG View
PRO Name ubiquitin-conjugating enzyme E2 D3 (human)
Definition A ubiquitin-conjugating enzyme E2 D3 that is encoded in the genome of human.
Short Label hUBE2D3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P61077 (UBE2D3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Acetylation IEDB 34357683
K8 Acetylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
S11 Phosphorylation PhosphoSitePlus
S83 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
T98 Phosphorylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K133 Acetylation PhosphoSitePlus
K133 Ubiquitination PhosphoSitePlus
K144 Acetylation PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
Y145 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation HPRD 20068231
S13 Phosphorylation HPRD   PhosphoSitePlus 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 P9 Biomuta DOID:1324 / lung cancer [ cosmic ]
S94 L94 Biomuta DOID:3571 / liver cancer [ cosmic ]
S105 F105 Biomuta [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
Y145 C145 Biomuta DOID:4159 / skin cancer [ cosmic ]