iPTMnet Report for P61018 (RAB4B)
Protein Information
UniProt AC / UniProt ID | P61018 / RAB4B_HUMAN |
Protein Name | Ras-related protein Rab-4B |
Gene Name | Name: RAB4B ORFNames:PP1596; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P61018 |
PRO Name | Ras-related protein Rab-4B (human) |
Definition | A Ras-related protein Rab-4B that is encoded in the genome of human. |
Short Label | hRAB4B |
Category | organism-gene |
P61018 (RAB4B) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
A2 | Acetylation | score1 | UniProt | 22223895 | ||
C23 | S-Nitrosylation | score0 | dbSNO | 24105792 | ||
K58 | Acetylation | score1 | PhosphoSitePlus | |||
K58 | Ubiquitination | score1 | PhosphoSitePlus | |||
T64 | Phosphorylation | score1 | PhosphoSitePlus | |||
C119 | S-Nitrosylation | score0 | dbSNO | 24105792 | ||
K123 | Ubiquitination | score1 | PhosphoSitePlus | |||
T132 | Phosphorylation | score1 | PhosphoSitePlus | |||
S137 | Phosphorylation | score1 | PhosphoSitePlus | |||
K172 | Ubiquitination | score1 | PhosphoSitePlus | |||
S185 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y189 | Phosphorylation | score1 | PhosphoSitePlus | |||
S193 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T64 | P64 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
T132 | P132 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
S137 | F137 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S193 | F193 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] |