Protein Information

Cytoscape View

UniProt AC / UniProt ID P60900 / PSA6_HUMAN
Protein Name Proteasome subunit alpha type-6
Gene Name Name: PSMA6
Organism Homo sapiens (Human)

PRO ID PR:P60900
DAG View
PRO Name proteasome subunit alpha type-6 (human)
Definition A proteasome subunit alpha type-6 that is encoded in the genome of human.
Short Label hPSMA6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P60900 (PSMA6) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
R3 Methylation PhosphoSitePlus
S5 Phosphorylation PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
R11 Methylation PhosphoSitePlus
T14 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus   UniProt 23186163
R21 Methylation PhosphoSitePlus
Y23 Phosphorylation PhosphoSitePlus
Y27 Phosphorylation PhosphoSitePlus
K30 Methylation PhosphoSitePlus
K30 Ubiquitination PhosphoSitePlus
K45 Acetylation PhosphoSitePlus
K45 Ubiquitination PhosphoSitePlus
K54 Ubiquitination PhosphoSitePlus
K55 Acetylation PhosphoSitePlus
K55 Sumoylation PhosphoSitePlus
K55 Ubiquitination PhosphoSitePlus
K59 Acetylation PhosphoSitePlus
K59 Ubiquitination PhosphoSitePlus
S63 Phosphorylation PhosphoSitePlus   UniProt 23186163
S64 Phosphorylation PhosphoSitePlus   UniProt 23186163
T65 Phosphorylation PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
T73 Phosphorylation PhosphoSitePlus
Y96 Phosphorylation PhosphoSitePlus
K102 Acetylation PhosphoSitePlus   UniProt 19608861
K102 Methylation PhosphoSitePlus
K102 Sumoylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
Y103 Phosphorylation PhosphoSitePlus
K104 Acetylation PhosphoSitePlus   UniProt 19608861
K104 Ubiquitination PhosphoSitePlus
Y105 Phosphorylation PhosphoSitePlus
Y107 Phosphorylation PhosphoSitePlus
K116 Acetylation PhosphoSitePlus
K116 Ubiquitination PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
C154 S-Nitrosylation dbSNO 19483679
Y159 Phosphorylation PhosphoSitePlus
Y160 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
C161 S-Nitrosylation dbSNO 19483679
K164 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
K181 Acetylation PhosphoSitePlus
K181 Ubiquitination PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K211 Ubiquitination PhosphoSitePlus
S213 Phosphorylation PhosphoSitePlus
T231 Phosphorylation PhosphoSitePlus
R245 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation HPRD 20068231
Y160 Phosphorylation HPRD 18083107

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
R3 H3 Biomuta DOID:11934 / head and neck cancer [ tcga ]
R11 L11 Biomuta DOID:3571 / liver cancer [ icgc ]
S63 F63 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K71 N71 Biomuta DOID:1612 / breast cancer [ cosmic ]
T73 N73 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
K102 N102 Biomuta DOID:1909 / melanoma [ tcga ]
K211 E211 Biomuta DOID:1909 / melanoma [ cosmic ]
R245 I245 Biomuta DOID:1324 / lung cancer [ cosmic ]
R245 T245 Biomuta DOID:11054 / urinary bladder cancer [ tcga ]