iPTMnet Report for P60880 (SNAP25)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P60880 / SNP25_HUMAN
Protein Name Synaptosomal-associated protein 25
Gene Name Name: SNAP25
Synonyms:SNAP;
Organism Homo sapiens (Human)

PRO ID PR:P60880
DAG View
PRO Name synaptosomal-associated protein 25 (human)
Definition A synaptosomal-associated protein 25 that is encoded in the genome of human.
Short Label hSNAP25
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P60880 (SNAP25) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation PhosphoSitePlus
T29 Phosphorylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
S115 O-Glycosylation GlyGen 30379171, 36240223
T138 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 22311984, 12459461, 17325194, ...14766180, 28486561
T138 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   Signor 12459461, 22311984
S187 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 22311984, 12459461, 17325194, ...14529723, 18171919
S187 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   Signor 12459461, 17325194, 18171919, ...22311984
Site PTM Type PTM Enzyme Score Source PMID
T138 Phosphorylation HPRD 12459461
T138 Phosphorylation P17252 (PRKCA) HPRD 12459461
T138 Phosphorylation P17612 (PRKACA) HPRD 12459461
S187 Phosphorylation HPRD 12459461
S187 Phosphorylation P17252 (PRKCA) HPRD 12459461
Site PTM Type PTM Enzyme Score Source PMID
K76 Acetylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
T138 Phosphorylation HPRD 12459461
T138 Phosphorylation P17252 (PRKCA) HPRD 12459461
T138 Phosphorylation P17612 (PRKACA) HPRD 12459461
S187 Phosphorylation HPRD 12459461
S187 Phosphorylation P17252 (PRKCA) HPRD 12459461


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S28 I28 Biomuta DOID:363 / uterine cancer [ icgc ]
K40 T40 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S115 R115 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S187 F187 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S187 T187 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]