iPTMnet Report for P60484 (PTEN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P60484 / PTEN_HUMAN
Protein Name Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
Gene Name Name: PTEN
Synonyms:MMAC1,TEP1;
Organism Homo sapiens (Human)

PRO ID PR:P60484
DAG View
PRO Name phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (human)
Definition A phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN that is encoded in the genome of human.
Short Label hPTEN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P60484 (PTEN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Ubiquitination PRO
T2 Acetylation UniProt 22814378
K6 Acetylation PhosphoSitePlus
K6 Ubiquitination PhosphoSitePlus
K13 Ubiquitination PhosphoSitePlus   UniProt 18716620
Y27 Phosphorylation PhosphoSitePlus 23995781
Y27 Phosphorylation P06213 (INSR) PhosphoSitePlus 23995781
Y46 Phosphorylation PhosphoSitePlus 22891331
Y46 Phosphorylation P12931 (SRC) PhosphoSitePlus 22891331
K60 Ubiquitination PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
Y68 Phosphorylation PhosphoSitePlus 22891331
Y68 Phosphorylation P12931 (SRC) PhosphoSitePlus 22891331
K80 Ubiquitination PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus   RLIMS-P 25701194
S113 Phosphorylation Q13315 (ATM) PhosphoSitePlus 25701194
K125 Acetylation PhosphoSitePlus
K128 Acetylation PhosphoSitePlus
Y138 Phosphorylation PhosphoSitePlus   RLIMS-P 19915616
Y155 Phosphorylation PhosphoSitePlus 22891331
Y155 Phosphorylation P12931 (SRC) PhosphoSitePlus 22891331
K163 Acetylation PhosphoSitePlus
K164 Acetylation PhosphoSitePlus
Y174 Phosphorylation PhosphoSitePlus 22891331, 23995781
Y174 Phosphorylation P06213 (INSR) PhosphoSitePlus 23995781
Y174 Phosphorylation P12931 (SRC) PhosphoSitePlus 22891331
Y176 Phosphorylation PhosphoSitePlus
Y177 Phosphorylation PhosphoSitePlus
Y178 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
Y180 Phosphorylation PhosphoSitePlus
K223 Ubiquitination PhosphoSitePlus
S227 O-Glycosylation GlyGen 30379171
S227 Phosphorylation PhosphoSitePlus
S229 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor 15793569
S229 Phosphorylation Q13464 (ROCK1) phospho.ELM   PhosphoSitePlus   Signor 15793569
T232 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor 15793569
T232 Phosphorylation Q13464 (ROCK1) phospho.ELM   PhosphoSitePlus   Signor 15793569
Y240 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 22891331, 11948419, 31025173
Y240 Phosphorylation P06239 (LCK) phospho.ELM   PhosphoSitePlus 11948419
Y240 Phosphorylation P07948 (LYN) PhosphoSitePlus 22891331
Y240 Phosphorylation P12931 (SRC) PhosphoSitePlus 22891331
Y240 Phosphorylation P21802 (FGFR2) PhosphoSitePlus   Signor 22891331
Y240 Phosphorylation P22607 (FGFR3) PhosphoSitePlus   Signor 22891331
K254 Sumoylation PhosphoSitePlus
K266 Sumoylation PhosphoSitePlus
K289 Sumoylation PhosphoSitePlus
K289 Ubiquitination PhosphoSitePlus   UniProt 18716620
S294 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
Y315 Phosphorylation phospho.ELM   PhosphoSitePlus   Signor 22891331, 11948419
Y315 Phosphorylation P06239 (LCK) phospho.ELM   PhosphoSitePlus   Signor 11948419
Y315 Phosphorylation P12931 (SRC) PhosphoSitePlus 22891331
T319 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 26166433, 28263967
T321 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 26166433, 28263967
K327 Ubiquitination PhosphoSitePlus
K332 Acetylation PhosphoSitePlus
Y336 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 19345329, 31043790, 34015051
Y336 Phosphorylation P42685 (FRK) neXtProt   PhosphoSitePlus 19345329
S362 Phosphorylation phospho.ELM   PhosphoSitePlus 16107342
S362 Phosphorylation P49841 (GSK3B) PhosphoSitePlus 16107342
T366 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 20940307, 17444818, 29608813, ...19208634, 26527737, 28263967, 30964887, 30456390, 23419777, 12297295, 16107342, 24275569
T366 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   Signor 16107342
T366 Phosphorylation Q9H4B4 (PLK3) neXtProt   PhosphoSitePlus   Signor 20940307
S370 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 20940307, 11035045, 21779440, ...19208634, 19629644, 26527737, 28263967, 25007873, 12297295, 16107342, 17444818
S370 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 19629644, 12297295, 16107342, ...21779440, 11035045
S370 Phosphorylation Q9H4B4 (PLK3) neXtProt   PhosphoSitePlus   Signor 20940307
Y377 Phosphorylation PhosphoSitePlus 22891331
Y377 Phosphorylation P12931 (SRC) PhosphoSitePlus 22891331
S380 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 22759359, 20610402, 17520061, ...28720772, 22074495, 24292679, 24858043, 25128467, 25771877, 32899927, 28400560, 18363844, 24625059, 19641606, 28415790, 32033487, 24063548, 25871383, 28878269, 24012691, 26222500, 33262514, 21819957, 24844349, 25277183, 23783762, 21565140, 32823607, 28442995, 28498467, 21779440, 26333042, 17562371, 26527737, 24706748, 22521126, 24098536, 10866658, 18321849, 24811168, 30455992, 30149868, 22413754, 36155262, 25925379, 11035045, 17158952, 19492080, 12077256, 32471246, 29221176, 25596747, 27362804, 18332125
S380 Phosphorylation P53350 (PLK1) PhosphoSitePlus 24706748
S380 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 11035045, 21779440
S380 Phosphorylation Q05513 (PRKCZ) PhosphoSitePlus 18321849
S380 Phosphorylation Q15831 (STK11) neXtProt   PhosphoSitePlus   Signor 18321849, 21779440
S380 Phosphorylation Q96KB5 (PBK) Signor 24012691
T382 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 22759359, 25881543, 25771877, ...32899927, 28400560, 19641606, 28415790, 32033487, 28878269, 24292679, 26222500, 33262514, 24844349, 32823607, 21779440, 26333042, 26527737, 24706748, 24098536, 10866658, 18321849, 30149868, 22413754, 36155262, 11035045, 17158952, 17562371, 25596747
T382 Phosphorylation P53350 (PLK1) PhosphoSitePlus 24706748
T382 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 11035045, 21779440
T382 Phosphorylation Q05513 (PRKCZ) PhosphoSitePlus 18321849
T382 Phosphorylation Q15831 (STK11) neXtProt   PhosphoSitePlus   Signor 18321849, 21779440
T383 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 22759359, 25771877, 18723495, ...28400560, 19641606, 17562371, 28878269, 24292679, 26222500, 33262514, 24844349, 21779440, 26333042, 26527737, 24706748, 24098536, 10866658, 18321849, 30149868, 22413754, 36155262, 11035045, 17158952, 28415790, 25596747
T383 Phosphorylation P53350 (PLK1) PhosphoSitePlus 24706748
T383 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 11035045, 21779440
T383 Phosphorylation Q05513 (PRKCZ) PhosphoSitePlus 18321849
T383 Phosphorylation Q15831 (STK11) neXtProt   PhosphoSitePlus   Signor 18321849
S385 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 32823607, 32033487, 30149868, ...22413754, 21779440, 11035045, 24292679, 26527737, 12077256, 23783762, 15987703, 12297295, 17565999, 16107342, 24098536
S385 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   Signor 11035045, 12297295, 16107342, ...21779440
S385 Phosphorylation Q15831 (STK11) Signor 15987703
T398 Phosphorylation IEDB   PhosphoSitePlus   RLIMS-P 30993208, 23888040
T398 Phosphorylation Q13315 (ATM) PhosphoSitePlus 23888040
T401 Phosphorylation PhosphoSitePlus   UniProt 10646847
K402 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K125 Acetylation PRO 10619020
K125 Acetylation PR:000012332 (KAT2B) PRO 10619020
K128 Acetylation PRO 10619020
K128 Acetylation PR:000012332 (KAT2B) PRO 10619020
Y240 Phosphorylation HPRD 11948419
Y315 Phosphorylation HPRD 11948419
T366 Phosphorylation HPRD 12297295
T366 Phosphorylation P19784 (CSNK2A2) HPRD 12297295
T366 Phosphorylation P68400 (CSNK2A1) HPRD 12297295
S370 Phosphorylation HPRD 12297295
S370 Phosphorylation P19784 (CSNK2A2) HPRD 12297295
S370 Phosphorylation P68400 (CSNK2A1) HPRD 12297295
S380 Phosphorylation HPRD 12077256, 10866658
S380 Phosphorylation P31749 (AKT1) HPRD 12077256, 10866658
T382 Phosphorylation HPRD 10866658
T383 Phosphorylation HPRD 10866658
S385 Phosphorylation HPRD 15987703, 12077256, 12297295
S385 Phosphorylation P31749 (AKT1) HPRD 12077256, 12297295
S385 Phosphorylation Q15831 (STK11) HPRD 15987703
K402 Acetylation PRO 18757404
K402 Acetylation PR:Q92793 (hCREBBP) PRO 18757404
Site PTM Type PTM Enzyme Score Source PMID
K235 Ubiquitination PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000048943 (hPTEN/UbiqLys+) ub PRO
PR:000028750 (hPTEN/iso:1/Ac:1) acK402 PR:Q92793 (hCREBBP) PRO 18757404
PR:000028805 (hPTEN/iso:1/Ac:2) acK125,acK128 PR:000012332 (KAT2B) PRO 10619020


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P60484 (PTEN) S380 P12830 (CDH1) inhibited_association eFIP 24811168
Phosphorylation P60484 (PTEN) T383 Q86UL8 (MAGI2) unknown eFIP 11431330
Phosphorylation P60484 (PTEN) T319 Q96QB1 (DLC1) unknown eFIP 26166433
Phosphorylation Q02750 (MAP2K1) T292 P60484 (PTEN) decreased_association eFIP 23453810


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K6 E6 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ]
K6 I6 Biomuta DOID:1319 / brain cancer [ cosmic ]
K6 N6 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
K6 R6 Biomuta DOID:1245 / vulva cancer [ cosmic ]
K6 T6 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K13 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
K13 E13 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:2394 / ovarian cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
K13 N13 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K13 Q13 Biomuta DOID:363 / uterine cancer [ cosmic ]
K13 T13 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y27 * Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic, tcga ]
Y27 C27 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic, icgc, tcga ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic ]
Y27 H27 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y27 N27 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
Y27 S27 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y27 D27 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic, icgc ] DOID:10534 / stomach cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ]
Y46 H46 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y46 D46 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y46 C46 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y46 * Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
K60 * Biomuta DOID:1319 / brain cancer [ cosmic ] DOID:3565 / meningioma [ cosmic ]
K60 T60 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K66 * Biomuta DOID:3119 / gastrointestinal system cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K66 Q66 Biomuta DOID:363 / uterine cancer [ cosmic ]
K66 N66 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
K66 E66 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
K66 T66 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y68 N68 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y68 H68 Biomuta [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic ] DOID:1793 / pancreatic cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
Y68 C68 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1319 / brain cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
Y68 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
K80 N80 Biomuta DOID:1319 / brain cancer [ cosmic ]
K80 E80 Biomuta DOID:1319 / brain cancer [ cosmic ]
S113 R113 Biomuta DOID:363 / uterine cancer [ cosmic ]
S113 T113 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
K125 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K125 E125 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
K125 N125 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
K125 T125 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K128 T128 Biomuta [ cosmic ]
K128 Q128 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K128 M128 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K128 N128 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
K128 * Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y138 D138 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
Y138 C138 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
Y138 S138 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
Y138 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y155 S155 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y155 C155 Biomuta [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, icgc, tcga ] DOID:2394 / ovarian cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
Y155 H155 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
Y155 N155 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
K163 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
K163 Q163 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K164 * Biomuta DOID:1324 / lung cancer [ cosmic ]
Y174 N174 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
Y174 H174 Biomuta DOID:1319 / brain cancer [ cosmic ]
Y174 D174 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:2394 / ovarian cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
Y174 C174 Biomuta DOID:4362 / cervical cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
Y174 * Biomuta DOID:184 / bone cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
Y176 C176 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
Y176 F176 Biomuta DOID:10534 / stomach cancer [ cosmic ]
Y176 * Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
Y177 * Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
Y177 S177 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y177 D177 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ]
Y177 F177 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
Y177 C177 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ]
Y177 H177 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
Y178 S178 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y178 H178 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y178 N178 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y178 C178 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y178 D178 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y178 F178 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y178 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]
S179 I179 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y180 * Biomuta DOID:2394 / ovarian cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K223 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S227 F227 Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
S229 * Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:4362 / cervical cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic ] DOID:1793 / pancreatic cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
S229 L229 Biomuta DOID:2174 / ocular cancer [ cosmic ]
T232 P232 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T232 A232 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ] DOID:2531 / hematologic cancer [ cosmic ]
Y240 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K254 * Biomuta DOID:363 / uterine cancer [ cosmic ]
K254 E254 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K266 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
K266 N266 Biomuta DOID:363 / uterine cancer [ icgc ]
K289 E289 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S294 N294 Biomuta DOID:1324 / lung cancer [ cosmic ]
S294 R294 Biomuta DOID:3565 / meningioma [ cosmic ]
S302 N302 Biomuta DOID:363 / uterine cancer [ cosmic ]
Y315 H315 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y315 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
K327 * Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:263 / kidney cancer [ cosmic ]
K332 * Biomuta DOID:1319 / brain cancer [ cosmic ]
Y336 * Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ] DOID:363 / uterine cancer [ cosmic, tcga ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ] DOID:4606 / bile duct cancer [ cosmic ]
Y336 F336 Biomuta DOID:1319 / brain cancer [ cosmic ]
T382 S382 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T398 S398 Biomuta DOID:10283 / prostate cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
T401 I401 Biomuta [ cosmic ] DOID:1319 / brain cancer [ cosmic ]