iPTMnet Report P58743 SLC26A5

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P58743 / S26A5_HUMAN
Protein Name	Prestin
Gene Name	Name: SLC26A5 Synonyms:PRES;
Organism	Homo sapiens (Human)

PRO ID	PR:P58743 DAG View
PRO Name	prestin (human)
Definition	A prestin that is encoded in the genome of human.
Short Label	hSLC26A5
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P58743 (SLC26A5) as Substrate

Expanded View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	N163	N-Glycosylation		score3	GlyGen	15140192, 19898896
	N166	N-Glycosylation		score3	GlyGen	15140192, 19898896
	K233	Acetylation		score1	PhosphoSitePlus
	Y237	Phosphorylation		score1	PhosphoSitePlus
	T360	Phosphorylation		score1	PhosphoSitePlus
	C381	Methylation		score1	IEDB	31844290
	S505	Phosphorylation		score1	PhosphoSitePlus
	Y526	Phosphorylation		score1	PhosphoSitePlus
	Y616	Phosphorylation		score1	PhosphoSitePlus
	S713	Phosphorylation		score1	IEDB	35494241

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S505	Phosphorylation		score0	HPRD	18452278
	Y526	Phosphorylation		score0	HPRD	18452278

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	S505	Phosphorylation		score0	HPRD	18452278
	Y526	Phosphorylation		score0	HPRD	18452278

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
N163	K163	Biomuta		DOID:4159 / skin cancer [ cosmic, icgc, tcga ]
S505	N505	Biomuta		DOID:1324 / lung cancer [ cosmic ]
S713	G713	Biomuta		DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]