iPTMnet Report for P58335 (ANTXR2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P58335 / ANTR2_HUMAN
Protein Name Anthrax toxin receptor 2 precursor
Gene Name Name: ANTXR2
Synonyms:CMG2;
Organism Homo sapiens (Human)

PRO ID PR:P58335
DAG View
PRO Name anthrax toxin receptor 2 (human)
Definition An anthrax toxin receptor 2 that is encoded in the genome of human.
Short Label hANTXR2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P58335 (ANTXR2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S81 Phosphorylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
T90 Phosphorylation PhosphoSitePlus
T96 Phosphorylation PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
T118 Phosphorylation PhosphoSitePlus
Y119 Phosphorylation PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus   UniProt 19690332
K161 Acetylation PhosphoSitePlus
T370 Phosphorylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K372 Ubiquitination PhosphoSitePlus
T375 Phosphorylation PhosphoSitePlus
S379 Phosphorylation PhosphoSitePlus
Y380 Phosphorylation PhosphoSitePlus
Y381 Phosphorylation PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
Y445 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
Y463 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S81 Phosphorylation HPRD 18452278
T90 Phosphorylation HPRD 18452278
S487 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S81 F81 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, cosmic, icgc ]
T118 A118 Biomuta DOID:4159 / skin cancer [ cosmic ]
K161 T161 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T375 P375 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K399 T399 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K449 N449 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]