iPTMnet Report for P58317 (ZNF121)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P58317 / ZN121_HUMAN
Protein Name Zinc finger protein 121
Gene Name Name: ZNF121
Synonyms:ZNF20;
Organism Homo sapiens (Human)

PRO ID PR:P58317
DAG View
PRO Name zinc finger protein 121 (human)
Definition A zinc finger protein 121 that is encoded in the genome of human.
Short Label hZNF121
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P58317 (ZNF121) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C25 Methylation IEDB 31844290
K69 Methylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K86 Ubiquitination PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
S91 Phosphorylation PhosphoSitePlus
T114 Phosphorylation PhosphoSitePlus
Y116 Phosphorylation PhosphoSitePlus
K119 Ubiquitination PhosphoSitePlus
C121 Methylation IEDB 31844290
S134 Phosphorylation PhosphoSitePlus
K147 Sumoylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
T165 Phosphorylation PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
K170 Ubiquitination PhosphoSitePlus
K175 Sumoylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K179 Ubiquitination PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
T223 Phosphorylation PhosphoSitePlus
K226 Ubiquitination PhosphoSitePlus
K235 Sumoylation PhosphoSitePlus
K254 Sumoylation PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
C270 Methylation IEDB 31844290
K272 Ubiquitination PhosphoSitePlus
T279 Phosphorylation HPRD   PhosphoSitePlus 20058876
C289 Methylation IEDB 31844290
K291 Sumoylation PhosphoSitePlus
T307 Phosphorylation PhosphoSitePlus
K315 Sumoylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
T333 Phosphorylation PhosphoSitePlus
T335 Phosphorylation PhosphoSitePlus
K338 Sumoylation PhosphoSitePlus
K338 Ubiquitination PhosphoSitePlus
K343 Ubiquitination PhosphoSitePlus
T363 Phosphorylation PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S87 F87 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
C121 R121 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S134 C134 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S134 F134 Biomuta DOID:363 / uterine cancer [ icgc ]
T223 I223 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K254 T254 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K272 N272 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T279 A279 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K338 N338 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
K385 Q385 Biomuta DOID:363 / uterine cancer [ icgc ]