iPTMnet Report for P57772 (EEFSEC)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P57772 / SELB_HUMAN
Protein Name Selenocysteine-specific elongation factor
Gene Name Name: EEFSEC
Synonyms:SELB;
Organism Homo sapiens (Human)

PRO ID PR:P57772
DAG View
PRO Name selenocysteine-specific elongation factor (human)
Definition A selenocysteine-specific elongation factor that is encoded in the genome of human.
Short Label hEEFSEC
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P57772 (EEFSEC) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S28 Phosphorylation PhosphoSitePlus
T30 Phosphorylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
C130 Methylation IEDB 31844290
K155 Ubiquitination PhosphoSitePlus
K166 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K332 Ubiquitination PhosphoSitePlus
T385 Phosphorylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
Y486 Phosphorylation PhosphoSitePlus
T498 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
T512 Phosphorylation PhosphoSitePlus
K527 Ubiquitination PhosphoSitePlus
K529 Ubiquitination PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus   UniProt 23186163
K542 Ubiquitination PhosphoSitePlus
T545 Phosphorylation PhosphoSitePlus
K549 Ubiquitination PhosphoSitePlus
R556 Methylation PhosphoSitePlus
R561 Methylation PhosphoSitePlus
K582 Methylation PhosphoSitePlus
K590 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T385 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T30 I30 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S511 F511 Biomuta DOID:4159 / skin cancer [ cosmic ]
K529 N529 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
R556 H556 Biomuta [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
R556 S556 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]