iPTMnet Report for P57739 (CLDN2)
Protein Information
| UniProt AC / UniProt ID | P57739 / CLD2_HUMAN |
| Protein Name | Claudin-2 |
| Gene Name | Name: CLDN2 ORFNames:PSEC0059,SP82,UNQ705/PRO1356; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P57739 |
| PRO Name | claudin-2 (human) |
| Definition | A claudin-2 that is encoded in the genome of human. |
| Short Label | hCLDN2 |
| Category | organism-gene |
DAG ViewP57739 (CLDN2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S192 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y194 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y195 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y198 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S208 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S223 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y224 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S225 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q16625 (OCLN) | S408 | P57739 (CLDN2) | unknown | eFIP | 21536752 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S192 | F192 | Biomuta | DOID:2531 / hematologic cancer [ cosmic, icgc ] |
