Protein Information

Cytoscape View


UniProt AC / UniProt ID P57739 / CLD2_HUMAN
Protein Name Claudin-2
Gene Name Name: CLDN2
ORFNames:PSEC0059,SP82,UNQ705/PRO1356;
Organism Homo sapiens (Human)

PRO ID PR:P57739
DAG View
PRO Name claudin-2 (human)
Definition A claudin-2 that is encoded in the genome of human.
Short Label hCLDN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P57739 (CLDN2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S192 Phosphorylation PhosphoSitePlus
Y194 Phosphorylation PhosphoSitePlus
Y195 Phosphorylation PhosphoSitePlus
Y198 Phosphorylation PhosphoSitePlus
S208 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
Y224 Phosphorylation PhosphoSitePlus
S225 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation Q16625 (OCLN) S408 P57739 (CLDN2) unknown eFIP 21536752


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S192 F192 Biomuta DOID:2531 / hematologic cancer [ tcga ]