iPTMnet Report for P57678 (GEMIN4)
Protein Information
| UniProt AC / UniProt ID | P57678 / GEMI4_HUMAN |
| Protein Name | Gem-associated protein 4 |
| Gene Name | Name: GEMIN4 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P57678 |
| PRO Name | gem-associated protein 4 (human) |
| Definition | A gem-associated protein 4 that is encoded in the genome of human. |
| Short Label | hGEMIN4 |
| Category | organism-gene |
DAG ViewP57678 (GEMIN4) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 19413330 | ||
| T13 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K36 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T84 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| S86 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T88 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C137 | Methylation | score1 | IEDB | 31844290 | ||
| K188 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K201 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S205 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus UniProt | 18669648 | ||
| T212 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K292 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K294 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S301 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K370 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K389 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K395 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K414 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C422 | Methylation | score1 | IEDB | 31844290 | ||
| C440 | Methylation | score1 | IEDB | 31844290 | ||
| S474 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C486 | Methylation | score1 | IEDB | 31844290 | ||
| K497 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K619 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K716 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K775 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C864 | Methylation | score1 | IEDB | 31844290 | ||
| C944 | Methylation | score1 | IEDB | 31844290 | ||
| T1018 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S1024 | Phosphorylation | score0 | HPRD | 20068231 | ||
| K1036 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T1050 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K1054 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| K36 | Q36 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| C137 | Y137 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| S205 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| K370 | M370 | Biomuta | DOID:184 / bone cancer [ cosmic ] | |
| C422 | W422 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| S474 | F474 | Biomuta | DOID:1612 / breast cancer [ cosmic ] | |
| K619 | N619 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| C864 | F864 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] |
