iPTMnet Report for P57103 (SLC8A3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P57103 / NAC3_HUMAN
Protein Name Sodium/calcium exchanger 3 precursor
Gene Name Name: SLC8A3
Synonyms:NCX3;
Organism Homo sapiens (Human)

PRO ID PR:P57103
DAG View
PRO Name sodium/calcium exchanger 3 (human)
Definition A sodium/calcium exchanger 3 that is encoded in the genome of human.
Short Label hSLC8A3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P57103 (SLC8A3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N45 N-Glycosylation GlyGen 29526322
Y64 Phosphorylation IEDB 35494241
T121 Phosphorylation PhosphoSitePlus
S426 Phosphorylation PhosphoSitePlus
Y430 Phosphorylation PhosphoSitePlus
T568 O-Glycosylation GlyGen 30379171
S629 Phosphorylation PhosphoSitePlus
S634 Phosphorylation PhosphoSitePlus
T643 Phosphorylation PhosphoSitePlus
T736 Phosphorylation IEDB 35494241
Site PTM Type PTM Enzyme Score Source PMID
T643 Phosphorylation HPRD 19664994, 18452278
Site PTM Type PTM Enzyme Score Source PMID
S629 Phosphorylation PhosphoSitePlus
T637 Phosphorylation HPRD 19664994, 18452278
Site PTM Type PTM Enzyme Score Source PMID
T640 Phosphorylation HPRD 19664994, 18452278
Site PTM Type PTM Enzyme Score Source PMID
T641 Phosphorylation HPRD 19664994, 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y64 N64 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
Y430 N430 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S629 T629 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S629 L629 Biomuta DOID:4159 / skin cancer [ cosmic ]
S634 F634 Biomuta DOID:4159 / skin cancer [ cosmic ]
T736 I736 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ]