Protein Information

Cytoscape View


UniProt AC / UniProt ID P57058 / HUNK_HUMAN
Protein Name Hormonally up-regulated neu tumor-associated kinase
Gene Name Name: HUNK
Synonyms:MAKV;
Organism Homo sapiens (Human)

PRO ID PR:P57058
DAG View
PRO Name hormonally up-regulated neu tumor-associated kinase (human)
Definition A hormonally up-regulated neu tumor-associated kinase that is encoded in the genome of human.
Short Label hHUNK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P57058 (HUNK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K56 Ubiquitination PhosphoSitePlus
S65 Phosphorylation PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K75 Ubiquitination PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K106 Ubiquitination PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
K327 Ubiquitination PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
S368 Phosphorylation PhosphoSitePlus
Y378 Phosphorylation PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
K483 Ubiquitination PhosphoSitePlus
S561 Phosphorylation PhosphoSitePlus
S585 Phosphorylation PhosphoSitePlus
T618 Phosphorylation PhosphoSitePlus
K674 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K188 E188 Biomuta DOID:1793 / pancreatic cancer [ tcga ] DOID:263 / kidney cancer [ tcga ]
K402 R402 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]