iPTMnet Report for P56937 (HSD17B7)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P56937 / DHB7_HUMAN
Protein Name 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7
Gene Name Name: HSD17B7
Synonyms:17HSD7;ORFNames:UNQ2563/PRO6243;
Organism Homo sapiens (Human)

PRO ID PR:P56937
DAG View
PRO Name 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 (human)
Definition A 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 that is encoded in the genome of human.
Short Label hHSD17B7
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P56937 (HSD17B7) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S118 Phosphorylation PhosphoSitePlus
T125 Phosphorylation PhosphoSitePlus
K176 Ubiquitination PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K190 Ubiquitination PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
Y198 Phosphorylation PhosphoSitePlus
C222 Methylation IEDB 31844290
K301 Ubiquitination PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
Y313 Phosphorylation PhosphoSitePlus
K315 Ubiquitination PhosphoSitePlus
K321 Acetylation PhosphoSitePlus
K321 Ubiquitination PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
S337 Phosphorylation PhosphoSitePlus
S339 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K188 E188 Biomuta DOID:3571 / liver cancer [ cosmic ]
K311 N311 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K311 Q311 Biomuta DOID:363 / uterine cancer [ icgc ]
K321 E321 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]