iPTMnet Report for P56856 (CLDN18)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P56856 / CLD18_HUMAN
Protein Name Claudin-18
Gene Name Name: CLDN18
ORFNames:UNQ778/PRO1572;
Organism Homo sapiens (Human)

PRO ID PR:P56856
DAG View
PRO Name claudin-18 (human)
Definition A claudin-18 that is encoded in the genome of human.
Short Label hCLDN18
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P56856 (CLDN18) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T68 Phosphorylation IEDB 31848261
N116 N-Glycosylation GlyGen 29671580
Y206 Phosphorylation PhosphoSitePlus
S210 Phosphorylation PhosphoSitePlus
Y211 Phosphorylation PhosphoSitePlus
S214 Phosphorylation PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
Y220 Phosphorylation PhosphoSitePlus
T229 Phosphorylation PhosphoSitePlus
Y241 Phosphorylation PhosphoSitePlus
T247 Phosphorylation PhosphoSitePlus
S253 Phosphorylation PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
Y260 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N116 N-Glycosylation PRO 29671580
Site PTM Type PTM Enzyme Score Source PMID
S97 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N116 I116 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S210 Y210 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y220 C220 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S256 F256 Biomuta DOID:1324 / lung cancer [ cosmic ]