Protein Information

Cytoscape View


UniProt AC / UniProt ID P56749 / CLD12_HUMAN
Protein Name Claudin-12
Gene Name Name: CLDN12
Organism Homo sapiens (Human)

PRO ID PR:P56749
DAG View
PRO Name claudin-12 (human)
Definition A claudin-12 that is encoded in the genome of human.
Short Label hCLDN12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P56749 (CLDN12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T111 Phosphorylation PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
S116 Phosphorylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
Y211 Phosphorylation PhosphoSitePlus
S216 Phosphorylation PhosphoSitePlus
Y220 Phosphorylation PhosphoSitePlus
S228 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20166139, 23186163
S231 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 19651622, 18669648, ...20166139, 19690332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S228 F228 Biomuta DOID:10283 / prostate cancer [ icgc ]
S231 F231 Biomuta DOID:10534 / stomach cancer [ icgc ]