iPTMnet Report for P56730 (PRSS12)
Protein Information
| UniProt AC / UniProt ID | P56730 / NETR_HUMAN |
| Protein Name | Neurotrypsin precursor |
| Gene Name | Name: PRSS12 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P56730 |
| PRO Name | neurotrypsin (human) |
| Definition | A neurotrypsin that is encoded in the genome of human. |
| Short Label | hPRSS12 |
| Category | organism-gene |
DAG ViewP56730 (PRSS12) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S270 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T276 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y486 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S495 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S637 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y766 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y777 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S778 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S270 | N270 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S270 | C270 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] | |
| T276 | M276 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| S637 | C637 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S637 | F637 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S637 | Y637 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
