iPTMnet Report for P56693 (SOX10)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P56693 / SOX10_HUMAN
Protein Name Transcription factor SOX-10
Gene Name Name: SOX10
Organism Homo sapiens (Human)

PRO ID PR:P56693
DAG View
PRO Name transcription factor SOX-10 (human)
Definition A transcription factor SOX-10 that is encoded in the genome of human.
Short Label hSOX10
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P56693 (SOX10) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
S17 Phosphorylation PhosphoSitePlus
S24 Phosphorylation PhosphoSitePlus   RLIMS-P   UniProt 19369195, 29315345
S27 Phosphorylation PhosphoSitePlus
S30 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus   RLIMS-P 29315345
K55 Sumoylation PhosphoSitePlus
K121 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K140 Acetylation PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
Y171 Phosphorylation PhosphoSitePlus
K172 Ubiquitination PhosphoSitePlus
K208 Acetylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus   RLIMS-P 29315345
S232 Phosphorylation PhosphoSitePlus   RLIMS-P 29315345
T240 Phosphorylation PhosphoSitePlus   RLIMS-P 29295999, 29315345
T244 Phosphorylation PhosphoSitePlus   RLIMS-P 29295999, 29315345
K246 Sumoylation PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
K357 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K172 E172 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S224 * Biomuta DOID:10534 / stomach cancer [ cosmic ]