Protein Information

Cytoscape View


UniProt AC / UniProt ID P56524 / HDAC4_HUMAN
Protein Name Histone deacetylase 4
Gene Name Name: HDAC4
Synonyms:KIAA0288;
Organism Homo sapiens (Human)

PRO ID PR:P56524
DAG View
PRO Name histone deacetylase 4 (human)
Definition A histone deacetylase 4 that is encoded in the genome of human.
Short Label hHDAC4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P56524 (HDAC4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T36 Phosphorylation PhosphoSitePlus
S45 Phosphorylation PhosphoSitePlus
S58 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus
S210 Phosphorylation Q13557 (CAMK2D) neXtProt   PhosphoSitePlus 17179159, 22360269
S215 Phosphorylation PhosphoSitePlus
Y225 Phosphorylation PhosphoSitePlus
Y233 Phosphorylation PhosphoSitePlus
K236 Acetylation PhosphoSitePlus
S246 Phosphorylation Q7KZI7 (MARK2) , P57059 (SIK1) , O43318 (MAP3K7) , Q16566 (CAMK4) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 24934156, 26305553, 16980613, ...27759007, 10869435, 17468767, 10958686
S265 Phosphorylation Q96GD4 (AURKB) neXtProt   PhosphoSitePlus   Signor 22865920
S266 Phosphorylation PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
S298 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   RLIMS-P   Signor 21118993
S302 Phosphorylation P49841 (GSK3B) PhosphoSitePlus   RLIMS-P   Signor 21118993
S339 Phosphorylation PhosphoSitePlus
S348 Phosphorylation PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus   UniProt 19690332, 22649097
T391 Phosphorylation PhosphoSitePlus
T394 Phosphorylation PhosphoSitePlus
S400 Phosphorylation PhosphoSitePlus
T465 Phosphorylation PhosphoSitePlus
S467 Phosphorylation Q16566 (CAMK4) , P57059 (SIK1) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 11470791, 26305553, 25728750, ...17468767, 18669648, 10958686
Y540 Phosphorylation PhosphoSitePlus
K548 Acetylation PhosphoSitePlus
K559 Sumoylation PhosphoSitePlus
S565 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S584 Phosphorylation PhosphoSitePlus
S611 Phosphorylation PhosphoSitePlus
S632 Phosphorylation Q13557 (CAMK2D) , Q16566 (CAMK4) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 11470791, 22042619, 26305553, ...23186163, 17179159, 22360269, 18669648, 24275569, 10958686
S633 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 22042619, 18669648
S636 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T638 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S642 Phosphorylation RLIMS-P 22042619
T648 Phosphorylation PhosphoSitePlus
S741 Phosphorylation PhosphoSitePlus
S744 Phosphorylation PhosphoSitePlus
S1025 Phosphorylation PhosphoSitePlus
T1057 Phosphorylation PhosphoSitePlus
S1061 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S210 Phosphorylation PR:Q13557-3 (hCAMK2D/iso:hDelta 3) PRO 17179159
S246 Phosphorylation PR:Q13557-3 (hCAMK2D/iso:hDelta 3) HPRD   PRO 17179159, 10869435, 10958686, ...20068231
S265 Phosphorylation HPRD 20068231
S266 Phosphorylation HPRD 20068231
T278 Phosphorylation HPRD 18491316
S467 Phosphorylation Q16566 (CAMK4) HPRD 11470791, 18669648
S565 Phosphorylation HPRD 19651622, 18669648, 20068231
S632 Phosphorylation Q16566 (CAMK4) HPRD 11470791, 19651622, 18669648, ...20068231
S633 Phosphorylation HPRD 18669648
S636 Phosphorylation HPRD 18669648
T638 Phosphorylation HPRD 18669648


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000029002 (hHDAC4/iso:1/Phos:1) pS210,pS246 PR:Q13557-3 (hCAMK2D/iso:hDelta 3) PRO 17179159


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:000029002 (hHDAC4/iso:1/Phos:1) Interaction PRO 17179159