iPTMnet Report for P56199 (ITGA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P56199 / ITA1_HUMAN
Protein Name Integrin alpha-1 precursor
Gene Name Name: ITGA1
Organism Homo sapiens (Human)

PRO ID PR:P56199
DAG View
PRO Name integrin alpha-1 (human)
Definition An integrin alpha-1 that is encoded in the genome of human.
Short Label hITGA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P56199 (ITGA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K81 Ubiquitination PhosphoSitePlus
N100 N-Glycosylation GlyGen   UniProt 19159218
N105 N-Glycosylation GlyGen   UniProt 19159218
N217 N-Glycosylation GlyGen   UniProt 19159218, 24190977
K274 Acetylation PhosphoSitePlus
N317 N-Glycosylation GlyGen 29741879
K328 Ubiquitination PhosphoSitePlus
N341 N-Glycosylation GlyGen   UniProt 19159218
N418 N-Glycosylation GlyGen   UniProt 29741879, 19159218, 24190977
T419 Phosphorylation PhosphoSitePlus
T420 Phosphorylation PhosphoSitePlus
S425 O-Glycosylation GlyGen 35289036
N460 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
Y527 Phosphorylation PhosphoSitePlus
N532 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 24190977
S541 Phosphorylation HPRD 20068231
Y604 Phosphorylation PhosphoSitePlus
T612 Phosphorylation PhosphoSitePlus
K709 Ubiquitination PhosphoSitePlus
N780 N-Glycosylation GlyGen   UniProt 19159218
S834 Phosphorylation PhosphoSitePlus
N840 N-Glycosylation GlyGen   UniProt 19159218, 24190977
N883 N-Glycosylation GlyGen 24190977
Y890 Phosphorylation PhosphoSitePlus
N966 N-Glycosylation GlyGen   UniProt 19159218
N974 N-Glycosylation GlyGen   UniProt 19159218
S992 Phosphorylation PhosphoSitePlus
S994 Phosphorylation PhosphoSitePlus
N1008 N-Glycosylation GlyGen   UniProt 19159218
K1046 Ubiquitination PhosphoSitePlus
N1102 N-Glycosylation GlyGen 24190977
N1113 N-Glycosylation GlyGen 29741879, 24190977


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K81 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K274 I274 Biomuta DOID:4159 / skin cancer [ cosmic ]
K274 T274 Biomuta DOID:5158 / pleural cancer [ cosmic ]
S425 C425 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
N966 S966 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
N974 D974 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N974 S974 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S994 F994 Biomuta DOID:4159 / skin cancer [ cosmic ]
S994 Y994 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:9256 / colorectal cancer [ icgc ]