iPTMnet Report for P56182 (RRP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P56182 / RRP1_HUMAN
Protein Name Ribosomal RNA processing protein 1 homolog A
Gene Name Name: RRP1
Synonyms:D21S2056E,NNP1,NOP52,RRP1A;
Organism Homo sapiens (Human)

PRO ID PR:P56182
DAG View
PRO Name ribosomal RNA processing protein 1 homolog A (human)
Definition A ribosomal RNA processing protein 1 homolog A that is encoded in the genome of human.
Short Label hRRP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P56182 (RRP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
T24 Phosphorylation PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
T204 Phosphorylation HPRD   PhosphoSitePlus 20068231
K205 Ubiquitination PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
T220 Phosphorylation HPRD   phospho.ELM 17081983
T238 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S245 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 24275569
S247 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 17081983
S250 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 17081983
S251 Phosphorylation PhosphoSitePlus   UniProt 21406692
K267 Ubiquitination PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
S383 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 19007248, 19691289
S391 Phosphorylation PhosphoSitePlus
T412 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19007248, 20068231
R423 Methylation PhosphoSitePlus
Q427 Methylation UniProt 26797129
T436 Phosphorylation PhosphoSitePlus
R444 Methylation PhosphoSitePlus
K455 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K205 N205 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T220 A220 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S251 Y251 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
S291 N291 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K330 T330 Biomuta DOID:363 / uterine cancer [ icgc ]