Protein Information

Cytoscape View

UniProt AC / UniProt ID P55895 / RAG2_HUMAN
Protein Name V(D)J recombination-activating protein 2
Gene Name Name: RAG2
Organism Homo sapiens (Human)

PRO ID PR:P55895
DAG View
PRO Name V(D)J recombination-activating protein 2 (human)
Definition A V(D)J recombination-activating protein 2 that is encoded in the genome of human.
Short Label hRAG2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P55895 (RAG2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
K88 Ubiquitination PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus
Y138 Phosphorylation PhosphoSitePlus
Y146 Phosphorylation PhosphoSitePlus
S291 Phosphorylation PhosphoSitePlus
S365 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus   RLIMS-P 17562296, 29069605
T490 Phosphorylation PhosphoSitePlus   RLIMS-P 12205088, 8146183, 29069605, ...8493533

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T121 N121 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S291 T291 Biomuta DOID:2531 / hematologic cancer [ icgc ]
S291 F291 Biomuta DOID:1324 / lung cancer [ cosmic ]