iPTMnet Report for P55895 (RAG2)
Protein Information
| UniProt AC / UniProt ID | P55895 / RAG2_HUMAN |
| Protein Name | V(D)J recombination-activating protein 2 |
| Gene Name | Name: RAG2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P55895 |
| PRO Name | V(D)J recombination-activating protein 2 (human) |
| Definition | A V(D)J recombination-activating protein 2 that is encoded in the genome of human. |
| Short Label | hRAG2 |
| Category | organism-gene |
DAG ViewP55895 (RAG2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K88 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T121 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y138 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y146 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S291 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S365 | Phosphorylation | P78527 (PRKDC) | score4 | neXtProt PhosphoSitePlus RLIMS-P | 17562296, 29069605 | |
| T490 | Phosphorylation | score4 | PhosphoSitePlus RLIMS-P | 12205088, 8146183, 29069605, ... |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T121 | N121 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| Y146 | C146 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| S291 | T291 | Biomuta | DOID:2531 / hematologic cancer [ cosmic ] | |
| S291 | F291 | Biomuta | DOID:4159 / skin cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] |
