iPTMnet Report for P55327 (TPD52)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P55327 / TPD52_HUMAN
Protein Name Tumor protein D52
Gene Name Name: TPD52
Organism Homo sapiens (Human)

PRO ID PR:P55327
DAG View
PRO Name tumor protein D52 (human)
Definition A tumor protein D52 that is encoded in the genome of human.
Short Label hTPD52
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55327 (TPD52) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S32 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S36 Phosphorylation PhosphoSitePlus
S40 Phosphorylation PhosphoSitePlus   RLIMS-P 35194188
K85 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K108 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
S115 Phosphorylation PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
K125 Ubiquitination PhosphoSitePlus
T131 Phosphorylation PhosphoSitePlus
T133 O-Glycosylation GlyGen 34019948, 28657654, 33465208
T133 Phosphorylation phospho.ELM 17287340
S134 O-Glycosylation GlyGen 31373491
S134 Phosphorylation PhosphoSitePlus
Y136 Phosphorylation PhosphoSitePlus
K137 Acetylation PhosphoSitePlus
K137 Ubiquitination PhosphoSitePlus
K138 Acetylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
S140 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
S144 Phosphorylation PhosphoSitePlus
K149 Ubiquitination PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S156 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
T162 Phosphorylation PhosphoSitePlus
K163 Acetylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K169 Ubiquitination PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
T173 Phosphorylation PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
S176 O-Glycosylation GlyGen 34019948, 28657654, 33465208
S176 Phosphorylation neXtProt   PhosphoSitePlus   Signor 20946871, 20032513, 18832449
S176 Phosphorylation Q13557 (CAMK2D) neXtProt   PhosphoSitePlus   Signor 20946871, 20032513, 18832449
K180 Ubiquitination PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K187 Ubiquitination PhosphoSitePlus
K192 Ubiquitination PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
K219 Ubiquitination PhosphoSitePlus
T220 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus   UniProt 18669648
Site PTM Type PTM Enzyme Score Source PMID
T131 Phosphorylation HPRD 20068231
Y136 Phosphorylation HPRD 20068231
T142 Phosphorylation HPRD 18767875
S159 Phosphorylation HPRD 18212344
S171 Phosphorylation HPRD 18669648, 17287340, 17081983, ...20068231
T173 Phosphorylation HPRD 18669648, 17287340, 20068231
S176 Phosphorylation HPRD 17287340, 18212344, 18452278, ...18669648, 18707149, 20166139, 20068231
S223 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T91 Phosphorylation HPRD 20068231
Y96 Phosphorylation HPRD 20068231
T102 Phosphorylation HPRD 18767875
S119 Phosphorylation HPRD 18212344
S131 Phosphorylation HPRD 18669648, 17287340, 17081983, ...20068231
T133 Phosphorylation HPRD 18669648, 17287340, 20068231
S136 Phosphorylation HPRD 17287340, 18212344, 18452278, ...18669648, 18707149, 20166139, 20068231
S183 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T91 Phosphorylation HPRD 20068231
Y96 Phosphorylation HPRD 20068231
T102 Phosphorylation HPRD 18767875
S119 Phosphorylation HPRD 18212344
S145 Phosphorylation PhosphoSitePlus
S147 Phosphorylation PhosphoSitePlus
S154 Phosphorylation HPRD   PhosphoSitePlus 20068231
T156 Phosphorylation HPRD 18669648
S159 Phosphorylation HPRD 18212344, 18452278, 18669648, ...18707149, 20166139, 20068231
S206 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S176 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S185 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S194 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S176 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S32 G32 Biomuta DOID:3571 / liver cancer [ cosmic ]
K102 N102 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S115 Y115 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S119 L119 Biomuta DOID:1324 / lung cancer [ cosmic ]
T133 S133 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T133 A133 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S136 * Biomuta DOID:1324 / lung cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
S140 C140 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S145 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S147 G147 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S155 L155 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T156 S156 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S159 L159 Biomuta DOID:1324 / lung cancer [ cosmic ]
S159 * Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic ]
T162 A162 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T173 S173 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S176 F176 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S176 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S178 G178 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K180 T180 Biomuta DOID:1793 / pancreatic cancer [ cosmic, icgc ]
S185 * Biomuta DOID:1612 / breast cancer [ cosmic ]
S187 G187 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K192 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S204 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]