Protein Information

Cytoscape View


UniProt AC / UniProt ID P55317 / FOXA1_HUMAN
Protein Name Hepatocyte nuclear factor 3-alpha
Gene Name Name: FOXA1
Synonyms:HNF3A,TCF3A;
Organism Homo sapiens (Human)

PRO ID PR:P55317
DAG View
PRO Name hepatocyte nuclear factor 3-alpha (human)
Definition A hepatocyte nuclear factor 3-alpha that is encoded in the genome of human.
Short Label hFOXA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55317 (FOXA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S165 Phosphorylation PhosphoSitePlus
Y166 Phosphorylation PhosphoSitePlus
S223 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
K237 Acetylation PhosphoSitePlus
K240 Acetylation PhosphoSitePlus
K264 Acetylation PhosphoSitePlus
K267 Acetylation PhosphoSitePlus
K270 Acetylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
S331 Phosphorylation PhosphoSitePlus   UniProt 24275569
S338 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
Y429 Phosphorylation PhosphoSitePlus
S448 Phosphorylation PhosphoSitePlus
Y464 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S282 Phosphorylation HPRD 20068231
S304 Phosphorylation HPRD 20068231
S307 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S234 C234 Biomuta DOID:1612 / breast cancer [ cosmic ]
K264 M264 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S282 R282 Biomuta DOID:2531 / hematologic cancer [ tcga ]
S395 C395 Biomuta DOID:10283 / prostate cancer [ cosmic ]
Y429 C429 Biomuta DOID:1612 / breast cancer [ cosmic ]