iPTMnet Report for P55316 (FOXG1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P55316 / FOXG1_HUMAN
Protein Name Forkhead box protein G1
Gene Name Name: FOXG1
Synonyms:FKH2,FKHL1,FKHL2,FKHL3,FKHL4,FOXG1A,FOXG1B,FOXG1C;
Organism Homo sapiens (Human)

PRO ID PR:P55316
DAG View
PRO Name forkhead box protein G1 (human)
Definition A forkhead box protein G1 that is encoded in the genome of human.
Short Label hFOXG1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55316 (FOXG1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K11 Acetylation PhosphoSitePlus
S19 Phosphorylation PhosphoSitePlus   RLIMS-P   Signor 19755996, 17435750
S19 Phosphorylation P48729 (CSNK1A1) PhosphoSitePlus   Signor 17435750
Y186 Phosphorylation PhosphoSitePlus
Y208 Phosphorylation PhosphoSitePlus
S228 Phosphorylation PhosphoSitePlus
S234 Phosphorylation PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
T279 Phosphorylation neXtProt   PhosphoSitePlus 17435750, 21228151
T279 Phosphorylation P31749 (AKT1) neXtProt   PhosphoSitePlus 17435750, 21228151
S280 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S19 I19 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S228 C228 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
S234 P234 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S234 A234 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
Y246 F246 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y254 N254 Biomuta DOID:3571 / liver cancer [ cosmic ]
T278 A278 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T279 I279 Biomuta DOID:4159 / skin cancer [ cosmic ]
T279 N279 Biomuta DOID:1324 / lung cancer [ cosmic ]
S280 * Biomuta DOID:1324 / lung cancer [ cosmic ]