iPTMnet Report P55273 CDKN2D

Protein Information

Cytoscape View

UniProt AC / UniProt ID	P55273 / CDN2D_HUMAN
Protein Name	Cyclin-dependent kinase 4 inhibitor D
Gene Name	Name: CDKN2D
Organism	Homo sapiens (Human)

PRO ID	PR:P55273 DAG View
PRO Name	cyclin-dependent kinase 4 inhibitor D (human)
Definition	A cyclin-dependent kinase 4 inhibitor D that is encoded in the genome of human.
Short Label	hCDKN2D
Category	organism-gene

Interactive Sequence View

	Select/align proteoforms across species

P55273 (CDKN2D) as Substrate

P55273

Condensed View

	Site	PTM Type	PTM Enzyme	Score	Source	PMID
	M1	Acetylation		score1	UniProt	12665801
	S66	Phosphorylation		score4	HPRD phospho.ELM PhosphoSitePlus RLIMS-P	19063602, 10734227, 29531090, ...32874495
	S76	Phosphorylation		score4	HPRD neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor	29531090, 22558186, 10734227, ...19063602, 32874495
	S76	Phosphorylation	P17252 (PRKCA)	score1	Signor	22558186
	S76	Phosphorylation	P24941 (CDK2)	score3	neXtProt PhosphoSitePlus Signor	22558186
	T84	Phosphorylation		score1	PhosphoSitePlus
	T89	Phosphorylation		score1	PhosphoSitePlus
	T141	Phosphorylation		score3	neXtProt PhosphoSitePlus RLIMS-P Signor	22558186
	T141	Phosphorylation	P17252 (PRKCA)	score1	Signor	22558186
	T141	Phosphorylation	P17612 (PRKACA)	score3	neXtProt PhosphoSitePlus	22558186
	T141	Phosphorylation	P24941 (CDK2)	score1	Signor	22558186

PTM sites affected in variants

Site	Variant	Source	PMID	Disease [Sample source]
T84	S84	Biomuta		DOID:9256 / colorectal cancer [ cosmic ]
T89	I89	Biomuta		DOID:363 / uterine cancer [ icgc ]