iPTMnet Report for P55268 (LAMB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P55268 / LAMB2_HUMAN
Protein Name Laminin subunit beta-2 precursor
Gene Name Name: LAMB2
Synonyms:LAMS;
Organism Homo sapiens (Human)

PRO ID PR:P55268
DAG View
PRO Name laminin subunit beta-2 (human)
Definition A laminin subunit beta-2 that is encoded in the genome of human.
Short Label hLAMB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55268 (LAMB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K86 Ubiquitination PhosphoSitePlus
Y232 Phosphorylation PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
N248 N-Glycosylation GlyGen 23090970, 24190977
C283 Methylation IEDB 31844290
K399 Ubiquitination PhosphoSitePlus
R464 Methylation PhosphoSitePlus
R468 Methylation PhosphoSitePlus
T477 Phosphorylation PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
C682 Methylation IEDB 31844290
K690 Ubiquitination PhosphoSitePlus
N1085 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S1181 O-Glycosylation GlyGen 34019948, 28657654, 35289036
N1249 N-Glycosylation GlyGen 23090970, 24190977
T1250 O-Glycosylation GlyGen 34019948, 28657654, 35289036
N1308 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
K1322 Ubiquitination PhosphoSitePlus
N1348 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
S1356 O-Glycosylation GlyGen 30459171
S1472 Phosphorylation PhosphoSitePlus
S1475 Phosphorylation PhosphoSitePlus
K1497 Ubiquitination PhosphoSitePlus
N1499 N-Glycosylation GlyGen   UniProt 23090970, 29741879, 19159218, ...24190977
S1532 Phosphorylation UniProt 26091039
S1548 Phosphorylation PhosphoSitePlus
K1603 Ubiquitination PhosphoSitePlus
S1654 Phosphorylation PhosphoSitePlus
S1655 Phosphorylation PhosphoSitePlus
K1671 Ubiquitination PhosphoSitePlus
R1674 Methylation PhosphoSitePlus
K1714 Ubiquitination PhosphoSitePlus
K1720 Sumoylation PhosphoSitePlus
K1720 Ubiquitination PhosphoSitePlus
K1748 Ubiquitination PhosphoSitePlus
Y1759 Phosphorylation PhosphoSitePlus
K1769 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y232 C232 Biomuta DOID:2394 / ovarian cancer [ cosmic ]
N248 S248 Biomuta DOID:1319 / brain cancer [ cosmic ]
S1181 L1181 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
N1249 H1249 Biomuta DOID:1612 / breast cancer [ cosmic ]
S1654 N1654 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S1655 F1655 Biomuta [ cosmic ]
K1671 T1671 Biomuta DOID:9256 / colorectal cancer [ cosmic ]