iPTMnet Report for P55263 (ADK)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P55263 / ADK_HUMAN
Protein Name Adenosine kinase
Gene Name Name: ADK
Organism Homo sapiens (Human)

PRO ID PR:P55263
DAG View
PRO Name adenosine kinase (human)
Definition An adenosine kinase that is encoded in the genome of human.
Short Label hADK
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55263 (ADK) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
K42 Ubiquitination PhosphoSitePlus
K47 Acetylation PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K51 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
Y77 Phosphorylation PhosphoSitePlus   UniProt 12112843
K111 Ubiquitination PhosphoSitePlus
K117 Ubiquitination PhosphoSitePlus
C160 S-Nitrosylation dbSNO 19483679
K162 Acetylation PhosphoSitePlus
K162 Sumoylation PhosphoSitePlus
K162 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
T246 Phosphorylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
K270 Acetylation PhosphoSitePlus
K274 Acetylation PhosphoSitePlus
C353 S-Nitrosylation dbSNO 2212679, 22126794, 24105792, ...26338901
Site PTM Type PTM Enzyme Score Source PMID
T83 Phosphorylation HPRD 20068231
Site PTM Type PTM Enzyme Score Source PMID
T66 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K63 M63 Biomuta DOID:263 / kidney cancer [ cosmic ]
K71 E71 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K274 N274 Biomuta DOID:4159 / skin cancer [ cosmic ]