iPTMnet Report for P55212 (CASP6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P55212 / CASP6_HUMAN
Protein Name Caspase-6 precursor
Gene Name Name: CASP6
Synonyms:MCH2;
Organism Homo sapiens (Human)

PRO ID PR:P55212
DAG View
PRO Name caspase-6 (human)
Definition A caspase-6 that is encoded in the genome of human.
Short Label hCASP6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55212 (CASP6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R9 Methylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K36 Acetylation PhosphoSitePlus
K36 Ubiquitination PhosphoSitePlus
S79 O-Glycosylation GlyGen 29351928
S79 Phosphorylation PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K144 Ubiquitination PhosphoSitePlus
K147 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
S257 Phosphorylation neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 32029622, 15273717, 22483120, ...22433863
S257 Phosphorylation O60285 (NUAK1) neXtProt   phospho.ELM   PhosphoSitePlus 15273717
K265 Ubiquitination PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
K273 Acetylation PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K284 Acetylation PhosphoSitePlus
K285 Acetylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S257 Phosphorylation HPRD 15273717
S257 Phosphorylation O60285 (NUAK1) HPRD 15273717


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K285 N285 Biomuta DOID:1324 / lung cancer [ cosmic ]