iPTMnet Report for P55160 (NCKAP1L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P55160 / NCKPL_HUMAN
Protein Name Nck-associated protein 1-like
Gene Name Name: NCKAP1L
Synonyms:HEM1;
Organism Homo sapiens (Human)

PRO ID PR:P55160
DAG View
PRO Name Nck-associated protein 1-like (human)
Definition A Nck-associated protein 1-like that is encoded in the genome of human.
Short Label hNCKAP1L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55160 (NCKAP1L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
K14 Ubiquitination PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
K42 Ubiquitination PhosphoSitePlus
K49 Ubiquitination PhosphoSitePlus
K56 Acetylation PhosphoSitePlus
K56 Ubiquitination PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
K61 Ubiquitination PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
C277 Methylation IEDB 31844290
S311 Phosphorylation PhosphoSitePlus
K313 Ubiquitination PhosphoSitePlus
Y315 Phosphorylation PhosphoSitePlus
K323 Ubiquitination PhosphoSitePlus
K326 Ubiquitination PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
C451 Methylation IEDB 31844290
S467 Phosphorylation PhosphoSitePlus
K500 Ubiquitination PhosphoSitePlus
C598 Methylation IEDB 31844290
S600 Phosphorylation PhosphoSitePlus
S624 Phosphorylation PhosphoSitePlus
K630 Ubiquitination PhosphoSitePlus
K638 Ubiquitination PhosphoSitePlus
T650 Phosphorylation PhosphoSitePlus
S671 Phosphorylation PhosphoSitePlus
Y747 Phosphorylation PhosphoSitePlus
K887 Ubiquitination PhosphoSitePlus
T909 Phosphorylation PhosphoSitePlus
C998 Methylation IEDB 31844290
K1035 Acetylation PhosphoSitePlus
S1086 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 Y2 Biomuta DOID:363 / uterine cancer [ icgc ]
K40 I40 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K49 * Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K60 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K61 R61 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K61 * Biomuta DOID:263 / kidney cancer [ cosmic ]
K323 N323 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K326 N326 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
C451 Y451 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S624 R624 Biomuta DOID:184 / bone cancer [ cosmic ]
T650 I650 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y747 C747 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
K887 N887 Biomuta [ cosmic ]
T909 N909 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T909 A909 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]