iPTMnet Report for P55084 (HADHB)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P55084 / ECHB_HUMAN
Protein Name Trifunctional enzyme subunit beta, mitochondrial precursor
Gene Name Name: HADHB
ORFNames:MSTP029;
Organism Homo sapiens (Human)

PRO ID PR:P55084
DAG View
PRO Name trifunctional enzyme subunit beta, mitochondrial (human)
Definition A trifunctional enzyme subunit beta, mitochondrial that is encoded in the genome of human.
Short Label hHADHB
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55084 (HADHB) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K72 Acetylation PhosphoSitePlus   UniProt 19608861
K72 Ubiquitination PhosphoSitePlus
T91 Phosphorylation PhosphoSitePlus
Y100 Phosphorylation PhosphoSitePlus
K181 Acetylation PhosphoSitePlus
K188 Acetylation PhosphoSitePlus   UniProt 19608861
K201 Acetylation PhosphoSitePlus
Y244 Phosphorylation PhosphoSitePlus
R247 Methylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
K253 Acetylation PhosphoSitePlus
K254 Ubiquitination PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
K272 Acetylation PhosphoSitePlus
K272 Ubiquitination PhosphoSitePlus
K277 Acetylation PhosphoSitePlus
K291 Acetylation PhosphoSitePlus
K293 Acetylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
Y336 Phosphorylation PhosphoSitePlus
Y342 Phosphorylation PhosphoSitePlus
K348 Acetylation PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
Y357 Phosphorylation PhosphoSitePlus
T359 Phosphorylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
K408 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S308 Phosphorylation HPRD 20068231
T356 Phosphorylation HPRD 20068231
T359 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K72 E72 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
Y100 C100 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K201 T201 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K268 E268 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]