iPTMnet Report for P55081 (MFAP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P55081 / MFAP1_HUMAN
Protein Name Microfibrillar-associated protein 1
Gene Name Name: MFAP1
Organism Homo sapiens (Human)

PRO ID PR:P55081
DAG View
PRO Name microfibrillar-associated protein 1 (human)
Definition A microfibrillar-associated protein 1 that is encoded in the genome of human.
Short Label hMFAP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55081 (MFAP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO
S2 Acetylation UniProt 22814378, 22223895
S30 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K43 Acetylation PhosphoSitePlus
Y47 Phosphorylation HPRD   PhosphoSitePlus 19413330
S52 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 18691976, 16565220, 19651622, 18669648, 20166139, 18452278, 19690332, 20068231
S53 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...17081983, 18691976, 16565220, 19651622, 18669648, 24275569, 20166139, 18452278, 19690332, 20068231
K65 Acetylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus   UniProt 23186163
S116 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19664994, 18318008, 18691976, ...21406692, 23186163, 16565220, 24275569, 17487921, 19690332, 19413330, 18220336, 20058876, 19651622, 18452278, 18491316, 17081983, 15302935, 19664995, 18669648, 20166139, 19415658, 20068231
S118 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18691976, 21406692, ...18491316, 23186163, 17081983, 18220336, 15302935, 17487921, 18452278, 19651622, 18318008, 18669648, 24275569, 20166139, 16565220, 19415658, 20068231
S132 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18452278, 19651622, 18669648, 19415658, 20166139, 15345747, 19690332, 20068231
S133 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 23186163, 17081983, ...15302935, 18452278, 19651622, 18669648, 20166139, 15345747, 19415658, 20068231
S175 Phosphorylation HPRD   PhosphoSitePlus 18452278
S179 Phosphorylation HPRD 18452278
S183 Phosphorylation HPRD   PhosphoSitePlus 18452278
K200 Acetylation PhosphoSitePlus
K200 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
K249 Sumoylation PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
S258 Phosphorylation HPRD   PhosphoSitePlus 20058876, 18452278
T267 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19562805, 19664994, 18318008, ...18691976, 21406692, 23186163, 16565220, 18452278, 24275569, 17487921, 19690332, 19413330, 20058876, 19651622, 17081983, 15302935, 19664995, 18669648, 20187088, 20166139, 19415658, 20068231
Y276 Phosphorylation PhosphoSitePlus
K280 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
K329 Ubiquitination PhosphoSitePlus
K336 Sumoylation PhosphoSitePlus
K340 Acetylation PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
Y356 Phosphorylation PhosphoSitePlus
K357 Ubiquitination PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus   UniProt 23186163
N370 N-Glycosylation GlyGen 24190977
K371 Ubiquitination PhosphoSitePlus
K376 Ubiquitination PhosphoSitePlus
K381 Sumoylation PhosphoSitePlus
K381 Ubiquitination PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus
K390 Acetylation PhosphoSitePlus
K390 Ubiquitination PhosphoSitePlus
T392 Phosphorylation PhosphoSitePlus
K415 Ubiquitination PhosphoSitePlus
S432 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19007248, ...20068231


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036278 (hMFAP1/Ac:1) acM1 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 * Biomuta DOID:4159 / skin cancer [ cosmic ]
K43 R43 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S132 N132 Biomuta DOID:363 / uterine cancer [ cosmic ]
K242 M242 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K381 N381 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S432 C432 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]