iPTMnet Report for P55060 (CSE1L)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P55060 / XPO2_HUMAN
Protein Name Exportin-2
Gene Name Name: CSE1L
Synonyms:CAS;
Organism Homo sapiens (Human)

PRO ID PR:P55060
DAG View
PRO Name exportin-2 (human)
Definition An exportin-2 that is encoded in the genome of human.
Short Label hCSE1L
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P55060 (CSE1L) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378, 22223895
K16 Ubiquitination PhosphoSitePlus
K17 Acetylation PhosphoSitePlus
K17 Ubiquitination PhosphoSitePlus
T18 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K67 Ubiquitination PhosphoSitePlus
K71 Ubiquitination PhosphoSitePlus
R89 Methylation PhosphoSitePlus
S112 Phosphorylation PhosphoSitePlus   UniProt 23186163
K158 Acetylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
S166 Phosphorylation PhosphoSitePlus
T185 Phosphorylation PhosphoSitePlus
T191 Phosphorylation PhosphoSitePlus
T255 Phosphorylation PhosphoSitePlus
K268 Ubiquitination PhosphoSitePlus
S269 Phosphorylation PhosphoSitePlus
C272 Methylation IEDB 31844290
K281 Acetylation PhosphoSitePlus
C344 S-Nitrosylation dbSNO 19483679
K346 Ubiquitination PhosphoSitePlus
R355 Methylation PhosphoSitePlus
S366 Phosphorylation PhosphoSitePlus
Y369 Phosphorylation PhosphoSitePlus
R371 Methylation PhosphoSitePlus
S377 Phosphorylation PhosphoSitePlus
T381 Phosphorylation PhosphoSitePlus
C387 S-Nitrosylation dbSNO 19483679
Y408 Phosphorylation PhosphoSitePlus
K425 Ubiquitination PhosphoSitePlus
Y432 Phosphorylation PhosphoSitePlus
K440 Ubiquitination PhosphoSitePlus
K445 Ubiquitination PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
K481 Ubiquitination PhosphoSitePlus
T562 Phosphorylation PhosphoSitePlus
S566 Phosphorylation PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
Y571 Phosphorylation PhosphoSitePlus
K574 Acetylation PhosphoSitePlus   UniProt 19608861
C623 Methylation IEDB 31844290
T698 Phosphorylation PhosphoSitePlus
K726 Ubiquitination PhosphoSitePlus
S789 Phosphorylation PhosphoSitePlus
Y797 Phosphorylation PhosphoSitePlus
K824 Acetylation PhosphoSitePlus   UniProt 19608861
K824 Ubiquitination PhosphoSitePlus
K832 Ubiquitination PhosphoSitePlus
S834 Phosphorylation PhosphoSitePlus
K840 Ubiquitination PhosphoSitePlus
K848 Ubiquitination PhosphoSitePlus
S904 Phosphorylation PhosphoSitePlus
K912 Ubiquitination PhosphoSitePlus
K925 Ubiquitination PhosphoSitePlus
S931 Phosphorylation PhosphoSitePlus   UniProt 23186163, 24275569
K934 Ubiquitination PhosphoSitePlus
C939 S-Nitrosylation dbSNO 19483679
S945 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T12 Phosphorylation HPRD 20068231
T18 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K16 N16 Biomuta DOID:363 / uterine cancer [ icgc ]
R89 * Biomuta DOID:363 / uterine cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S377 C377 Biomuta DOID:1324 / lung cancer [ cosmic ]
S471 L471 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y571 D571 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
C623 R623 Biomuta DOID:3565 / meningioma [ cosmic ]
K925 R925 Biomuta DOID:3571 / liver cancer [ cosmic ]