Protein Information

Cytoscape View

UniProt AC / UniProt ID P55055 / NR1H2_HUMAN
Protein Name Oxysterols receptor LXR-beta
Gene Name Name: NR1H2
Organism Homo sapiens (Human)

PRO ID PR:P55055
DAG View
PRO Name oxysterols receptor LXR-beta (human)
Definition An oxysterols receptor LXR-beta that is encoded in the genome of human.
Short Label hNR1H2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P55055 (NR1H2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
T11 Phosphorylation PhosphoSitePlus
K31 Sumoylation PhosphoSitePlus
R126 Methylation PhosphoSitePlus
S200 Phosphorylation PhosphoSitePlus
K247 Ubiquitination PhosphoSitePlus
K409 Sumoylation PhosphoSitePlus
S426 Phosphorylation Q9UQM7 (CAMK2A) PhosphoSitePlus 21331046
K447 Sumoylation PhosphoSitePlus
K447 Ubiquitination PhosphoSitePlus

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 F8 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K31 N31 Biomuta DOID:363 / uterine cancer [ tcga ]
R126 W126 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]