iPTMnet Report for P55040 (GEM)
Protein Information
| UniProt AC / UniProt ID | P55040 / GEM_HUMAN |
| Protein Name | GTP-binding protein GEM |
| Gene Name | Name: GEM Synonyms:KIR; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P55040 |
| PRO Name | GTP-binding protein GEM (human) |
| Definition | A GTP-binding protein GEM that is encoded in the genome of human. |
| Short Label | hGEM |
| Category | organism-gene |
DAG ViewP55040 (GEM) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S23 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S57 | Phosphorylation | score1 | PhosphoSitePlus | |||
| C198 | Methylation | score1 | IEDB | 31844290 | ||
| Y255 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S261 | Phosphorylation | score3 | HPRD phospho.ELM PhosphoSitePlus | 14701738 | ||
| S261 | Phosphorylation | Q05513 (PRKCZ) | score2 | PhosphoSitePlus | 14701738 | |
| K276 | Acetylation | score1 | PhosphoSitePlus | |||
| K279 | Acetylation | score1 | PhosphoSitePlus | |||
| S287 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S289 | Phosphorylation | score3 | HPRD phospho.ELM PhosphoSitePlus | 14701738 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S23 | G23 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| S57 | R57 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S261 | R261 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
| S289 | F289 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
